Comparative Loco-Regional Analgesia using Lidocaine Alone and Lidocaine-Tramadol Mixture on Some Physiological Parameters in Goats Undergoing Rumenotomy
Comparative Loco-Regional Analgesia using Lidocaine Alone and Lidocaine-Tramadol Mixture on Some Physiological Parameters in Goats Undergoing Rumenotomy
Nura Abubakar1, Abubakar Sadiq Yakubu1, Salisu Buhari1, Adamu Abdul Abubakar2,1*, Mohammad Sani Ismaila3,4, Hassan Abubakar Bodinga1, Hassan Yahaya Nawawi5, Ashiru Dahiru6, Shehu Zaid7, Umar Salisu Ahmad1, Umar Abubakar Uwais8, Kabiru Zaki9
ABSTRACT
This study aimed to compare the time of onset, duration of action, and effects of subcutaneous lidocaine alone and lidocaine-tramadol combination on physiological parameters (pulse rate, respiratory rate, and rectal temperature) in goats undergoing an invasive surgical procedure. Sixteen (N=16) adult Red Sokoto goats weighing 20-26kg were used in the study and were randomly allocated into two groups: A and B. Group A animals received subcutaneous 2% lidocaine (7mg/kg) using an “inverted L” technique and group B received local infiltration with lidocaine-tramadol (3.5 mg/kg and 1.5 mg/kg respectively) using an “inverted L” technique. Following anesthesia, a rumenotomy was performed on each animal. Physiological parameters were measured at 0 hours (before drug administration) and then six times after drug administration at one-hour intervals while the rumenotomy was ongoing. There was a significant difference in the onset and duration of action between the lidocaine alone and lidocaine-tramadol-treated groups (P<0.05). There was a significant difference in pulse rate 1 hour after lidocaine administration; however, the lidocaine-tramadol group showed no significant change in the pulse rate throughout the experiment. It can be concluded that lidocaine or its combination with tramadol has no adverse effect on physiological parameters in goats undergoing rumenotomy.
Keywords | Loco-regional, Analgesia, Lidocaine-tramadol, Physiological parameters, Rumenotomy
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