Effect of Remimazolam Combined with Propofol Anesthesia on Perioperative Cellular Immunity in Patients Undergoing Laparoscopic Ovarian Cyst Surgery
Effect of Remimazolam Combined with Propofol Anesthesia on Perioperative Cellular Immunity in Patients Undergoing Laparoscopic Ovarian Cyst Surgery
Xintao Dai1, Zhenfeng Cai1, Xingli Jiang2 and Pinglei Wu1*
ABSTRACT
The aim of this study is to investigate the effects of remimazolam and propofol anesthesia on perioperative immune cell levels in patients undergoing laparoscopic ovarian cyst surgery (LOCS). The sample of 90 LOCS patients was randomly divided to an experimental group (EG) and a control group (CG) (45 per group). Participants in the CG were operated under propofol anesthesia, while in the EG it was under remimazolam anesthesia on the basis of the CG. The levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and blood oxygen saturation (SpO2) in the CG were lower than those in the EG during and after anesthesia. After 72 h, SAS in the EG was lower than those in the CG. Compared with the effect of propofol alone, the implementation of remimazolam anesthesia in LOCS patients was significant and could shorten the time of anesthesia-related indicators, and the level of vital sign changes during anesthesia was relatively more stable and had a smaller effect on the perioperative cellular immune level.
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