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HER2/neu Levels, Premature Termination of Pregnancy and Breast Cancer Risk: A Hospital-Based Study from Lahore, Pakistan

HER2/neu Levels, Premature Termination of Pregnancy and Breast Cancer Risk: A Hospital-Based Study from Lahore, Pakistan

Muhammad Mansha1*, Sidra Yaqub1, Asma Abdul Latif2, Muhammad Wasim3 and Peter C. Thomson4

1Department of Zoology, University of Education, Lahore, Pakistan.
2Department of Zoology Lahore College for Women University, Lahore
3Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore
4School of Life and Environmental Sciences, University of Sydney, Australia.

*      Corresponding author: dr.mansha@ue.edu.pk

Fig. 1.

Number of pregnancies (A), age of first pregnancy (B) and Number of children (C) of breast cancer patients, who were admitted to INMOL Hospital.

Fig. 2.

Distribution of HER2/neu for case and control groups.

Fig. 3.

ROC curve for HER2/neu expression as a diagnostic test for breast cancer (BC). Values below a HER2/neu threshold are indicative of BC. The blue dot on the curve indicates the optimal test (maximum Youden index, J = Se + Sp – 1.

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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