Pathogenicity and Immunogenicity Study of Infectious Bursal Disease 098 Bogor ’19 Virus Isolate as a Master Seed Candidate for Live IBD Vaccine
Pathogenicity and Immunogenicity Study of Infectious Bursal Disease 098 Bogor ’19 Virus Isolate as a Master Seed Candidate for Live IBD Vaccine
I Wayan Wisaksana Yasa1, I Wayan Teguh Wibawan2, Okti Nadia Poetri2*
Survival rate graph of IBD 098 Bogor ’19 and vvIBD 078 Lampung ’18 inoculation group.
Pathology anatomy observe of the vvIBD 078 Lampung ’18 group that experienced post-inoculation mortality. (a) Petechiae haemorrhage on the thigh muscle ; (b) Hypertrophy of bursa fabricious with accompanied by yellowish gelatinous accumulation and haemorrhage and (c) Renal hypertrophy accompanied by accumulation of uric acid.
Graph result of (a) Bursal body weight ratio (BBWR); (b) Index of Bursal body weight ratio (IBBWR); (c) Bursal lesion scoring (BLS). The value is expressed in mean (± standard deviation). The difference in the significance value of P<0.05 is considered significant.
Comparison of bursa fabricious histopathological observation of bursa fabricious in group (a) IBD 098 Bogor ’19, (b) IBD 078 Lampung ’18; (c) K (-).100× microscope magnification.
IBD ELISA mean titer (± standard deviation). The value of P<0.05 is significantly different and the value of P<0.01 is considered very significantly different.
