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Incidence of Hepatitis B and C Viruses in Thalassaemia Major Patients

Ahmad Farooq¹, Usman Waheed^2,3, Hasan Abbas Zaheer^2,3, Abdul Rauf⁴, Abida Arshad⁵, and Muhammad Arshad^1,*

...h the professional blood donors are a great risk but major concern is related to screening techniques and different laboratories are practicing variable quality of screening blood screening. All diagnostic techniques must be regulated under a standard quality control and a nation wise validation study is highly recommended.

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In-Silico Development of 1, 7-Dihydrodipyrrolo [2,3-b:3’,2’-e] Pyridine -3-carboxamide Derivatives as Candidate Janus Kinase Inhibitors to Control Rheumatoid Arthritis

Neelam Pery*, Nayab Batool Rizvi, Muhammad Imtiaz Shafiq

...osition of hydrogen bond donors and acceptors, it can accommodate the conformational changes of the binding cavity while maintaining interactions with the ATP binding residues. The designed inhibitors show some selectivity for JAK 1 and 3 over JAK2 offering a better safety profile against the harmful effects of JAK2 inhibition.

Prevalence of Torque Teno Virus in Blood Donors and its Implication on Blood Safety in Pakistan

Nosheen Basharat¹, Usman Waheed^2,3*, Muhammad Arshad¹, Noor e Saba⁴, Iram Masood¹, Akhlaaq Wazeer¹, Ahmad Farooq¹, Sadaf Moneeba¹, Abdul Rauf⁵ and Hasan Abbas Zaheer^2,3

... of TTV in healthy blood donors and find its relationship with hepatitis B and hepatitis C seropositivity. The study was conducted at the Department of Pathology and Transfusion Medicine, Shaheed Zulfiqar Ali Medical University, Islamabad, from November 2016 to June 2017. Total 282 samples were selected after routine blood screening of Hepatitis B and C, of which 75 were HCV positive (asymptomatic), 75 were HBV positive (asymptomatic) and 132 were from healthy...

HBV and HCV Seroprevalence in Hospital Admissions for Thalassemia Major in Bengbu, China

Jun Zhang¹*, Xiaocao Xu² and Min Cao²

...g and selection of blood donors the prevalence of HBV infection in high-risk patients has sharply decreased in recent years. Vaccination is one of the most important protective factors in this group of the population. Therefore, administration of a reminder dose based on antibody titer is recommended in these individuals.

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Anti-A and Anti-B Titer Among Blood Group O Donors at a Tertiary Care Centre Lahore, Pakistan

Anum Syyam^1,2, Nazish Saqlain¹, Sidra Hareem¹, Naghmana Mazhar¹, Liaqat Ali³ and Samia Afzal²*

...dies among blood group O donors at a tertiary care hospital. This is a cross-sectional study conducted at the department of Hematology and Transfusion Medicine in Children’s Hospital and the Institute of Child Health, Lahore, Pakistan over a period of four months from Oct, 2019 to Feb, 2020. Blood samples were collected from 350 healthy and voluntary group “O” donors (males = 320 and females = 30, median ag...

In-vitro Ruminal Ecosystem in Buffaloes on Concentrates and Fat Supplementation

Amirul Faiz Mohd Azmi1,4, Hafandi Ahmad1, Norhariani Mohd Nor1, Goh Yong Meng1, Mohd Zamri Saad2, Md Zuki Abu Bakar1, Norafizah Abdul Rahman5,6, Agung Irawan7,9, Anuraga Jayanegara8,9, Hasliza Abu Hassim1,3,9*

...e used as rumen contents donors. The in-vitro ruminal fermentation and microbial population profiles were investigated. The study revealed that Diet C had the highest ether extract and gross energy, with optimum value of crude proteins but low in crude fiber compared to diets B and A. Total volatile fatty acids (TVFA) and their molars proportion, gas production, total fatty acids, total bacteria count, and total protozoa count increased in parallel with the co...

Effects of Different Quick-Freezing Methods and Storage Temperatures on the Content of Cryoprecipitated Blood Coagulation Factors in Fresh Plasma

Haiyan Wen¹*, Kai Liao¹, Zhengrong Yuan² and Ning Zhou²

...ood from 60 unpaid blood donors who entered the blood station from January 2022 to October 2022. The acquisition time is controlled within 10 min. The plasma samples were divided into six groups (A, B, C, D, E, F) by using a random number table, 10 in each group. Group A (plate freezer for 30 min, - 30 ℃ storage), Group B (plate freezer for 30 min, 4 ℃ storage), Group C (plate freezer for 120 min, - 30 ℃ storage), Group D (plate freezer for 120 min, - 4 ...

Association of c.974C>G Mutation in Growth Differentiation Factor 9 with Recovery Rate in Peranakan Ongole Cattle

Irma¹*, Siti Darodjah Rasad², Nena Hilmia², Cece Sumantri³

...t was conducted using 21 donors from Livestock Embryo Centre (LEC), which were selected for the superovulation based on oestrous synchronization. The normality distribution of data was evaluated using Kolmogorov-Smirnov, followed by non-parametric analysis. Furthermore, Single Nucleotide Polymorphism (SNP) was used to determine genotypes and their association was analyzed with the Kruskal-Wallis statistical test. In PO, SNP c.974C>G on GDF9 showed that GG g...