Zahir Shah, Shakoor Ahamd, Mian Saeed Sarwar, Murad Ali Khan and Javid Ali
...mnesis revealed that the healing was complete in 14 days with no recurrence and untoward consequences....
Ann Milliken Pederson
...ople long for wholeness, healing, transformation, and an encounter with the ultimate. Ted Peters’ new book locates the vocation of humankind within their cosmic home, brings together the disciplines (humanities, social sciences, natural sciences) into a holistic integration of knowledge, places the quest and the question of God within the historical narrative of the natural and cultural history of the entire cosmos, and offers a vision of hope and action...
Pin Lyu1, Xiangxian Chen2* andQinlong Liu3*
...ur groups namely natural healing (control), exercise and massage, massage only and exercise only and received acute skeletal contusion to the right tibialis anterior, followed by corresponding rehabilitation methods. The injured muscular tissues and blood samples were collected pre-injury and post-injury on day 1, 2, 4, 6, 9, 12 and 15. The exercise and massage group showed the fastest recovery reflected by muscular histological structure and C-reactive protei...
Muhammad Naeem Khan* and Asad Jan
...d digestive problems and healing of wounds. The aim of the study was to explore phytochemical constituents of methanolic crude extract (MCE) and various solvent fractions and in-vitro antimicrobial activities of whole plant of D. botrys. Qualitative phytochemical screening of MCE and solvent fractions of D. botrys showed the presence of alkaloids, phenols, flavonoids, saponins, tannins and sterols, however in n-hexane fraction (HxF) only flavonoids and saponin...
Waqas Ahmad Shams1*, Gauhar Rehman1, Khurshaid Khan1, Ibrar Ahmad1, Saima Bibi1, Saif Ul Islam2, Dawood Safi1, Saba Gul Ayaz1
...alcium supplement and in healing of other injuries is also proven. In the present study, the diversity and abundance of crabs from Buner district of Khyber Pakhtunkhwa Pakistan were looked over, over a period of three years extending from June 2013 till June 2016, collected at different sampling points. Extensive surveys were conducted for three years at different timings during the active periods of crab life. To have a comprehensive study of the crab fauna o...
Magbolah Salem Helal Alzahrani
...rties. The plant’s healing properties come from its flowers, which contain volatile oils including bisabolol, bisabolol oxides A and B, and matricin as well as flavonoids. This study aims to elucidate the possible therapeutic applications of different levels of M. chamomilla on the functional status of liver, in rats injected with carbon tetrachloride (CCl4), a known hepatotoxin. Thirty-six male albino rats were treated with subcutaneou...
Taqiur Rahman1, Tabassum Yaseen1*, Ali Mujtaba Shah2, Samiullah3, Ghulam Jelani3, Gul Nawaz1,Qudratullah Kalwar2
...e vera L use for the healing of wounds, Arisaema jacquemontii blume used as antidote, Artimizia annua used asanathematize also in gastric problems, Avena sativa L. used as a laxative and antiseptic (R1).
Qiang Tang1 and Qianli Tang2*
...f isoliquiritin on wound healing in scalded rats. The results show that at 24 h after the last administration, wound healing rate of isoliquiritin group was higher than that of model group (p=0.024). Compared with control group, thickness of epidermis and dermis in model group was thinner (p<0.001), and width of subdermal collagen fibers also decreased (p<0.001), inflammatory factors TNF-α, I...
Monoar Pallab*, Moktadir Reza and Debashish Sarker
... prevent adhesion during healing. Muscle and skin were closed by interrupted and continuous sutures respectively. The animal recovered without any complications three weeks post-operatively....
Bingjie Zhou1, Hitesh Bhagavanbhai Mangukiya1, Siva Bharath Merugu1, Fakhar-un-Nisa Yunus1, Yuchen Fan1, Zhenghua Wu1,* and Dawei Li1,2,*
... proliferation and wound healing assays, while the auto-fluorescent property of DsRed was confirmed by fluorescence microscopy and immunofluorescence. The potential application of his-AGR2-DsRed was demonstrated by its internalization in fibroblasts. Therefore, the purified recombinant fluorescent protein would be a very useful tool for further investigation of AGR2’s extracellular function and molecular mechanism.
...
Rosidah Rosidah1*, Angga Nugraha1, Yuli Andriani1, Kiki Haetami1, Olga Anne2 and Agus Heri Purnomo3
... A. hydrophila by healing relatively fast body damage, response to feed and shock is normal and fast.
... 
Hafiz Muhammad Tahir*, Iram Liaqat*, Junaid Nadeem, Hammad Aamir and Shaukat Ali
... as well as aid in wound healing....
Muhammad Awais1,2, Waqas Ahmad3, Akhtar Rasool Asif4, Sayyed Aun Muhammad1, Iahtasham Khan1*, Muhammad Amjad Ali5, Muhammad Qaiser Riaz1 and Muhammad Saqib2
...>of illnesses and healingof wounds. A total of 40 rabbits were divided into four groups (A, B, C, and D) to perform two experiments. Two wounds of full-thickness with the dimensions of 1×1 cm (1 cm2), were created on right and left lateral sides of the trunk, comprising 4 wounds on each rabbit. Wounds of group A, B, C and D were treated with pyrogen free normal saline, 0.05% PI gel, certified Acacia honey and H-PImxr (an equal volume mi...
Nabila Rasheed1*, Bushra Waseem1, Kanwal Haneef2, Shumaila Usman3, Madeeha Sadiq1, Tabinda Urooj1, Sarah Tarique2 and Dabeeran Zeha4
...nalysis of viability and healing properties of GDM affected WJMSCs (GDM-WJMSCs) with Normal controls (N- WJMSCs). Mesenchymal stromal cells were isolated from Wharton’s jelly of human umbilical cords from normal and gestational diabetic mothers. Cell viability was tested by trypan blue exclusion method and wound healing potential by scratch assay method. Healing of the scratch was ob...
Chunjie Song1, Shangquan Gan2 and Xiaoyun Shen1,3*
... Yujin powder group. The healing rates were 75%, 85%, and 60% in low-dose group, high-dose group, gentamicin sulfate group, respectively. The effects of modified Yujin powder was better than gentamicin sulfate. The contents of blood urea nitrogen (BUN), malondialdehyde (MDA), and the number of white blood cell (WBC) in 3 drug delivery groups were extremely significantly lower (P<0.01) than the control group, and the contents of potassium (K), total protein ...
Zahra Jamilah Sabrina1, Adrian Pearl Gunawan2, Beryl Reinaldo Chandra2, Ilham Pangestu Harwoko3, Johannes Marulitua Nainggolan4,Widi Nugroho1*
...used to improve fracture healing, but flaws limit their use. Xenograft from micro-carbonated hydroxyapatite (micro-CHA) and nano-CHA from bovine bone combined with Platelet-Rich Plasma (PRP) was hypothesized to accelerate fracture healing. This study aimed to characterise micro-CHA and nano-CHA synthesized from bovine bone and analyze their effects as xenografts on fracture healing in Ratt...
Qi Zhuo, Yuanchun Yao, Meisongzhu Yang*, Jinhua Chen and Miao Tian
...ell proliferation; wound healing test and transwell assay were used to evaluate the ability of breast cancer cells to metastasize and invade; colony formation test was conducted to detect the effect of HDAC8 on the cells. We found that the expression of miR-216b-5p protein in breast cancer group was lower than that in healthy control group (P<0.05); the expression of HDAC8 protein in the group was higher than that in healthy control group (P<0.05). The M...
Al-Hassan M. Mostafa1*, Gehan Mohammed Sayed2
...s contortus which aid in healing process. However, the time that Coriandrum sativum needs for repairing affected tissue is relatively more than that of Allium sativum.
Keywords | Goat, Haemonchus contortus, Garlic, Coriander and abomasum.
...
Dhiya Altememy1, Mohammad Darvishi2*, Samira Shokri3, Saber Abbaszadeh4
... an effective remedy for healing wound infections in diabetics.
Keywords | Nanoparticle, Herbal plants, Diabetes, Staphylococcus aureus, Treatment
...
Eighty Mardiyan Kurniawati1*, Budi Santoso1, Fedik Abdul Rantam2, Widjiati3, Budi Iman Santoso4, Tri Hastono Setyo Hadi1, Gatut Hardianto1, Hari Paraton1
... reached 100%. The wound healing process needs to be supported by certain ingredients such as regenerative medicine. Amnion is easy to find and rich in growth substances. Aim: This study analyzed the comparison of tissue structure in the remodeling phase of the vesicovaginal fistula between the use of freeze-dried amnion and primary suturing on day 21. Materials and Methods: This experimental study used New Zealand rabbits which were female and weighed 3-4.5 k...
Mohamed M. Bahr1, Mohamed S. Amer1*, Khaled Abo-EL-Sooud2, Shaimaa M. Kamel3, Marwa A. Fouly4, Ahmed N. Abdallah5, Ashraf A. Shamaa1, Omar S. El-Tookhy1
Falah Mahmood Hameed1*, Asaad Khalaf Talal AL-Shuwaili2, Eman Jawad Jabber3, Mayada Sahib Hassan1
... that the speed of wound healing in treated rabbits were faster than non-treated rabbits. Additionally, the findings showed that treated groups had improved cellularity and expanded angiogenesis compared to non-treated group. Conclusion: The histological results supported the hypothesis that chitosan enhances and promotes the development of wound healing on the skin. ...
Kazi Afsana Homayra Orchy1, Mst. Antora Akter1, Nelema Yesmin1, Md. Moshiur Rahman Khan1, Marzia Rahman2, Md. Mahmudul Alam1*
...celerates the burn wound healing with no adverse effects ...
Reza Esmaealzade Dizaji1, Arasb Dabbagh Moghaddam1*, Arash Ghalyanchi Langeroudi2, Mohamad Foad Heydari3, Seyyed Javad Hosseini Shokouh4 and Ana Shirzad Shahrivar5
...egree heat wound and the healing process’ sub-streaming molecular route for re-epithelialization. Model (deep second-degree thermal wound), PRP, and PRP/BNF groups were each randomly assigned a set of animals. Wounds were monitored daily for many days following therapy to see how they were healing. H&E staining and qRT-PCR were used to examine the pathological alterations in wound tissues and to determine mRNA expr...
Nida Sadaqat1, Sheheyar Ahmed Khan1, Amna Bibi1, Sadaf Zahra1, Muhammad faisal Salamt1, Noreen Latief2 and Fatima Ali1*
...f time on rat skin wound healing were investigated. The NAC treatment promoted an improvement of wound healing by reducing the oxidative stress, improving wound closure, reducing tissue inflammation with no significant change in blood parameters. There were no significant differences in weekly and final body weights and no significant changes observed in hematological and biochemical markers. A significant increase in collag...
Fatima Ali1*, Rimsha Tahir1 and Tahir Rehman Samiullah2
...ay. Improvement in wound healing was also confirmed by analyzing angiogenesis, apoptosis and chemotaxis genes. A significant increase was observed in the percentage of wound contraction and significant decrease in the period of epithelialization in honey+3% NAC group as compared with control group. Histologically, honey+3% NAC Group treatment resulted in almost complete re-epithelialization and re-structuring of the wound tissue. There was a significant rise i...
Mohammed M. Jassim, Mohammed R. Abduljaleel*, Zainab B. Abdulkareem, Noor H. Sanad, Ibrahim M.H. Alrashid
...otional impacts upon the healing of the bone of the static electro-magnetic fields (PEMF) were well demonstrated, static magnetic fields (SMF) effects had stayed unclear. The effects of a specially constructed magnetic wrap on the histological and radiographic features of bone healing using a femoral rabbit model with an unstable osteotomy space and an implant have been investigated in the current work. After avian bone impl...
Rana Mahmood Ahmad*, Orooba M.S. Ibrahim
...tory response during the healing process. The histopathological observation showed that a section of a joint in groups treated with SaZnONPs had a normal joint cavity with normal articular cartilage compared with other treated groups. Accordingly, the findings of the present study suggested that ZnONPs reinforced with clove can be anti-arthritis treatments and may be utilized as a substitute for medicines currently on the market. ...
Abdul Aziz1,2, Hamad Bin Rashid1*, Muhammad Arif Khan1, Asim Khalid Mahmood1, Ayesha Hassan1, Hamid Akbar1, Sadaf Imran1, Naveed Hussain1, Muhammad Umar1, Muhammad Asif1, Sajjad Javaid1 and Mamoona Chaudhry3
Rana Mahmood Ahmad*, Orooba Mohammed Maeed Ibrahim
...tory response during the healing process. On the other hand, the positive control groups showed no improvement in the level of the anti-inflammatory cytokine (IL-10) in serum. According to the results, we can conclude that the clove oil produced using the petroleum ether have the potential to be used as an excellent anti-inflammatory agent with less side effect. Because medicinal plant extracts are non-toxic, safe, and have no harmful side effects, available i...
Johan Sukweenadhi1*, Stefan Pratama Chandra1, Finna Setiawan2, Christina Avanti2, Kartini Kartini2, Arief Koeswanto3 and Deok-Chun Yang4
...> L. extract helps wound healing in diabetic mice and is not significantly different from wound dressings and silver dressings on the market (p-value < 0.05). In addition, the best concentration that can be formulated into the dermal patch is 0.005% (p-value <0.05).
...
Saddam Hummadi1, Nadia Al-Falahi2*
...osite for accelerate the healing of infected wounds and improve cosmetic outcomes. A 5% w/v SIS hydrogel was prepared and formulated with 100 µg/ml AgNPs to evaluate its effect on healing of infected wounds in rabbit. Forty eight adult rabbits aged 8-12 months, weighing 1.5-2.5 kg, were divided randomly into three equal groups (n=16) after inducing infected wounds. In control group (GI), the infected wounds were manag...
Muhammad Talha Sajjad1, Hamid Akbar1*, Muhammad Arif Khan1, Muhammad Hassan Mushtaq3, Shehla Gul Bokhari1, Muhammad Abid Hayat4 and Ghulam Mustafa2
...P gel on cutaneous wound healing in rescued horses. Twelve horses were divided into two groups: group A (PRP-treated) and group B (control). The group A (n=6) animals were treated with autologous PRP gel, while the group B (n=6) animals were treated with sterile saline. Full-thickness (3 x 3 cm2) skin wounds were selected in each horse on either left or right region of back. Neovascularization was assessed on days 14 and 28 by color Doppler ultrasonography and...
Qamer J. Jadoaa, Raffal A. Omar*
...imulatory effect on bone healing in which osteogenic tissue and trabecular bone were noticed clearly at the end of 1st week, which achieves histologically compared to Diclofenac and control groups.
Keywords | Lidocaine hydrochloride, Diclofenac, Bone healing, Histological analysis, Intraosseous injection
...
Wafa’a Mohammad Abduwhab1*, Waseem Ali Hasan2, Mohanad Abdulsataar AL-Bayati3*
... third-degree burn wound healing. The reformulation of standard pumpkin seed oil involved the encapsulation of conventional Lidocaine within a phytosome structure, resulting in the formation of nanoparticles. This modification was undertaken to enhance both the physical stability of the oil and the therapeutic properties of pumpkin seed oil, while simultaneously mitigating the potential side effects associated with Lidocaine. Evaluation of the therapeutic effe...
Nabaa Fadhil Abbas*, Raffal A. Omar
...mifentanil on burn wound healing in rabbits. The research involved 30 rabbits divided into five groups: G1 (Lidocaine), G2 (Tramadol), G3 (Remifentanil), and two groups that received combinations of remifentanil with epinephrine. Additionally, one group received remifentanil in a gel formulation. After local administration of these substances by infiltration (s/c) and compared with the control group. the severity of the burn injury and subsequent
Abdul Asim Farooq1,2*, Muhammad Arif Khan1, Hamid Akbar1,
Muhammad Ashraf3, Saima Inayat4, Muhammad Usman Saleem5,
Saeed Murtaza2, Maqbool Hussain Shah2 and Muhammad Arshad Javid5
... to heal or show delayed healing that leads to intensified morbidity. Bone marrow aspirate (BMA) has been suggested as an efficient biological adjuvant for healing long bone fractures. BMA comprises bone mesenchymal stem cells. This study aims to assess the potential of autologous BMA on metacarpal and metatarsal fracture of Beetal goats presented at the surgery clinic of the University of Veterinary and Animal Sciences Laho...
Shakeel Haider Zaidi and Anwar Ahmad Khan
...plant in reputed for its healing
and anti-inflammatory properties and is largely used in
indigenous and allopathic medicines. To assess the
possibility of its introduction and cultivation as a
special crop, yield trials with various spacings were
conducted for 3 consecutive year (1989 to 1992) at
Medicinal plants farm, Peshawar. The plant has
successfully adapted to the climatic condition of
Peshawar giving the highest yield when planted at 60*30
cm s...
Naveed Hussain1*, Muhammad Arif Khan1, Asim Khalid Mahmood2, Muhammad Yasin Tipu3, Mamoona Chaudhry4, Hamad Bin Rashid1, Haroon Akbar5 and Abdul Aziz6
...s bone graft for osseous healing has been considered gold standard for decades. It contains viable osteoprogenitor cells, cytokines and growth factors with appropriate tissue matrix resulting in osteogenesis, osteoinduction and osteoconduction. Orthobiologics are biological materials used to augment bone and soft tissue cure, with multifactorial effects. In our study, three orthobiologics i.e., Bone Marrow Aspirate (BMA), Platelet Rich Plasma (PRP) and Decellu...
Hong Chen1,2, Jiawei Liu1,2, Chuan Lin1,2, Hao Lv1,2, Jiyun Zhang1,2, Xiaodong Jia1,2, Qinghua Gao1,2 and Chunmei Han1,2*
...c stimuli to promote the healing and rapid growth of wounded antlers....
Bunga Rimta Barus1, Masfria Masfria2*, Aminah Dalimunthe3, Sovia Lenny4
...aves in facilitating the healing process of excision wounds. The study utilized 30 male Wistar rats, divided into six groups with five rats each, to ensure robust statistical analysis. The ethyl acetate fraction was extracted using a detailed maceration and fractionation process with 96% ethanol, followed by formulation into a gel. The gel formulations were evaluated for their antimicrobial properties and effectiveness in facilitating wound
Hasan Ali Al-Sailawi1, Araa Ali Hadi1, Hussein A. Raheem2, Mustafa Mudhafar3,4, Sahi J Dhahi5, Qais R. Lahhob6*
MohamadRahijan AbdulWahab*andAhmadAimanSalahudin
...omoting health and wound healing. However, few studies have beenconducted on factors determining stingless bee honey consumption. This study aims to ascertain customer satisfaction, attitude, and purchase intent with reference to Seremban, Negeri Sembilan, and stingless bee honey consumption. The study’s other goals include figuring out how attitude and customer satisfaction are related, as well as how sociodemographic characteristics affect these variab...
Krishna Adhikari1, Suman Poudel1 and Manoj K. Shah2
...on of wound and fracture healing and return to functional mobility of the limb. The radiographic and physical examination on the 12th week showed cortical union, no signs of fracture lines, and absence of bridging callus on the alignment, with the dog being able to walk normally and bear proper weight on the affected limb, respectively. The IM Steinmann pin was removed from the affected limb in the 20th week following pin migration....
Syarifah Nurul Waqiah1, Ratmawati Malaka2*, Ambo Ako2, Sadam Suliman Mohamed Yousof3, Hanif Uzwa Hasanah Sudirman4
...es (Piper betle Linn) on healing wounds in dairy cattle and determine the herbal spray’s compounds. This study was conducted in August 2022, located in Cendana District, Enrekang Regency. The study method was a completely randomized design (CRD). The variables observed were the measurement of wound area (cm), wound drying time (days), wound healing time (days), the content of saponins (exist/not exist), tannins (%), fl...
Heba Saleh Shaheed1, Zainab J. Malik2*, Ghusoon A.A. Alneamah1, Salih T.H.2
Saad Ahmad1, Shahbaz ul Haq1, Shujaat Hussain2, Khurram Ashfaq1, Shahrood Ahmed Siddiqui3,4, Arsalan Khan5*, Abubakar Yameen1, Muhammad Wasim Usmani6, Rafiq Ullah7 and Muhammad Arslan Aslam1*
...ext-align: justify;">The healing of cutaneous wounds is a fundamental aspect of surgical procedures, with traditional suturing being the most common method of closure. However, novel techniques such as Photochemical Tissue Bonding (PTB) have emerged, offering potential improvements in healing outcomes. This study aimed to compare the efficacy of PTB, utilizing Rose Bengal dye and monochromatic green light, with that of conve...
Noura El-Kattan1*; Kamilia A.M. Allam2
Novel Research in Microbiology Journal (2021), 5(6): 1447-1462
...melling, delayed and non-healing wound infections. Six genera of bacteria were isolated from the collected swab samples, and then identified using conventional biochemical methods and API 20 kits. Staphylococcus aureus was found to be the most prevalent isolate (26.1 %), following by Pseudomonas aeruginosa (25.2 %), Klebsiella pneumonia (23.5 %), Acinetobacter baumannii (12.2 %), Proteus vulgaris (7.8 %), and the less common isolate of Escherichia coli (5.2 %)...
Umar Salisu Ahmad1,2*, Adamu Zoaka Hassan2, Echiobi Gaba Emmanuel2, Munir Ari Sani2, Fatai O. Anafi3, Adamu Abdul Abubakar4,1
...s are often removed post-healing, necessitating a second, costly surgery that can impact patient well-being. To avoid this, a bioabsorbable/biodegradable material (xenograft) is needed.This experimental study aimed to evaluate the effects of implanting camel bones into rat muscle tissue, comparing findings with a control group that had Kirschner wire (inert) implants. The study involved haematological and histological assessments of the implants and surroundin...
Hao Weng, Liang Zhu, Zhu Mei, Mingxian Wu and Qiang Xu*
...roup (CG) (favorable FNF healing, n=100) and an observation group (OG) (non-union FNFs, n=34). Levels of interleukin (IL)-1, IL-6, IL-8, C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-α) were compared at preoperative (D0), postoperative day 1 (D1), postoperative day 7 (D7), postoperative month 1 (M1), postoperative month 3 (M3), and postoperative month 6 (M6). The Harris hip joint functional score was assessed preoperatively and 6 months ...
Sayra Tariq, Zeeshan Mutahir and Moazzam Ali*
...es was observed in wound healing assay carried out with both MDA-MB-231/wt and epirubicin resistant cells. Percentage healing after 24 h with 10µM epirubicin alone was 38.1% for MDA-MB-231/epi-R cells. This further decreased to 32.35% when cells were exposed to 10µM epirubicin loaded on iron oxide nanoparticles. This study shows the ability of iron oxide nanoparticle-based drug delivery system for carrying the dr...
Pakistan Journal of Zoology
November
Featuring
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Exploring Helicobacter pylori’s Impact on Clinical Manifestations and Gastroesophageal Reflux Disease Spectrum
Syed Rafiq Hussain Shah, Atta Ullah, Dhafer Hazip Gaber Alwayli, Jiaxu Liang, Tayyab Saeed Akhter, Faisal Rasheed, Nimra Zafar Siddiqui, Bibi Nazia Murtaza and Wen Shu
Pakistan J. Zool., Vol. 56, pp. 3487-3499
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Genotoxicity and Anti-Cancer Activity of Tamoxifen and Ivermectin Loaded Chitosan Nanoparticles Against MCF-7 Cell Line
Usama Bin Naeem, Muhammad Adil Rasheed, Muhammad Ashraf and Muhammad Yasir Zahoor
Pakistan J. Zool., Vol. 56, pp. 3477-3486
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Morphometric Measurements, Gonopod and Gonopores Appearances in Early Sexual Crablet Stage of Scylla paramamosain (Estampador, 1949)
Muhammad Nur Syafaat, Che Zulkifli Che-Ismail, Adnan Amin-Safwan, Mohamad N. Azra, Mohammad Syahnon, Ambok Bolong Abol-Munafi and Mhd Ikhwanuddin
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 759-766
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Preparation of High Selenized Gastrodia elata Blume Polysaccharide and its Immunomodulatory Effects on RAW264.7 Cells and Cyclophosphamide-Treated Mice
Fengwei Ma, Qihua Wen, Qingfang Deng, Yihao Lu, Buyan Zhang, Yongyou Cheng and Su Xu
Pakistan J. Zool., Vol. 57, Iss. 2, pp. 747-758
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