High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

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High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

Bo Gao^1,2, Fengmei Yang³, Wei Chen², Xiaojia Song⁴, Xiaobo Liu⁵ and Dongmin Li¹*

Author Affiliations

¹Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shanxi 710061, P.R. China.

²Department of Laboratory Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.

³Department of Obstetrics and Gynecology,Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.

⁴Shiyan Prefecture Center for Disease Control and Prevention, Shiyan, Hubei 442000, P.R. China.

⁵Department of Gastroenterology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.

Bo Gao and Fengmei Yang contributed equally.

* Corresponding author: [email protected]

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Fig. 1.

The relative expression levels of MDR1 in all tissues.

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Fig. 2.

Recurrence time and survival time in different groups. PEOC: primary epithelial ovarian cancer; NSCLC: non-small cell lung cancer; MDR1: multidrug resistance 1; MDR1+: MDR1 positive group; MDR1-: MDR1 negative group.

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Fig. 3.

The ROC analysis of MDR1 expression and tumor markers in the prognosis of common malignant tumor.

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Fig. 4.

Survival curves of MDR1 mRNA-positive and negative patients. A: non-small cell lung cancer; B: colorectal cancer; C: primary epithelial ovarian cancer; D: gastric cancer; E:breast cancer.

This Issue

August 2020

Vol. 52, Iss. 4, Pages 1225-1630

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High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

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High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

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High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

High Expression of MDR1 is Correlated with Poor Prognosis for Common Malignancies

Bo Gao1,2, Fengmei Yang3, Wei Chen2, Xiaojia Song4, Xiaobo Liu5 and Dongmin Li1*

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Bo Gao^1,2, Fengmei Yang³, Wei Chen², Xiaojia Song⁴, Xiaobo Liu⁵ and Dongmin Li¹*