Jixue Hou1,2, Xueling Chen3, Jing Wang4, Hongwei Zhang2, Yu Xi2, Jie Xia2, Xinyu Peng2,* and Xiangwei Wu2,5*
...iologic process of cardiovascular disease, but for a long time it is just limited to large animals, like pigs, rabbits, and big rats. The mice with reproduction fast cycle, lower costing, and close to human genes, can be showed about some phenomenon quickly, also more easy to form model of atherosclerosis. Thus, a mouse model of vascular injury is vitally important for researching the pathophysiological mechanisms to resteno...
Sana Irshad Khan1*, Zafar Iqbal2, Hamid Ullah Shah2 and Shaukat Hussain3
...gus against the selected vascular Wilt causing fungus and bacteria, i.e. Fusarium oxysporum (87.50 ± 0.11% inhibition), Xanthomonas campestris (67.00 ± 0.46% inhibition) and Clavibacter michiganensis (72.00 ± 1.02% inhibition). The A. flavus was grown on two different media, i.e. Potato Dextrose Broth (PDB) and Glucose Nutrient Broth (GNB) media for active secondary metabolites. Ethyl acetate (EtOAc) extract of PDB medium gave significant ...
K.N. ArulJothi1, M. Abinaya1, B. Suruthi Abirami1, Melvin George2, S. Elangovan3 and A. Devi1*
...and development of cardiovascular disease (CVD) in different populations. In this study, we investigated the association of rs5888 polymorphism with serum lipid levels and CVD risk in an Indian population. A total of 412 samples which included 148 myocardial infarction survivors, 162 Normolipidemic healthy controls and 102 patients with hypercholesterolemia in a Indian Tamilian population were included in the study. Genotyping of SCARB1 genetic p...
P.P. Ghosh*, C. Ghosh, B. Mahato, A. Chakraborty, S.K. Bhattacharya and M.K. Bhattacharjya
...nt micro-level situation vascular bacterial wilt malady can be addressed by prophylactic application of lime at 500 kg/ha and bleaching powder 20 kg/ha in the soil four weeks before transplanting followed by seed dressing with 20g bioinoculant formulation per kg seed, pre-transplanting seedling root treatment with 20g bioinoculant formulation per litre and spot soil application of 7 days old mixture of bioinoculant formulation and well rotten cow-dung manure (...
A. Hamid1,*, M. Ilyas2 and S. Kalsoom3
...rolemia leading to cardiovascular diseases are very common problem in Pakistan and in most cases it is caused due to insufficient intake of dietary fiber.A study was conducted to evaluate the role of dietary fiber and ß-glucan from major food grains used locally on plasma cholesterol level of dietary-induced hypercholesterolemic rats. Insoluble dietary fiber (lignin and cellulose) was extracted from wheat and maize, while ß glucan was extracted fro...
Sanjukta Chakrabarti1, Colin J. Barrow2, Rupinder K. Kanwar3, Venkata Ramana1*, Rakesh N. Veedu4,5 and Jagat R. Kanwar3*
... angiogenic processes is vascular endothelial growth factor (VEGF) protein and its family of ligands and receptors (VEGFRs). Survival, proliferation, migration and invasion of endothelial cells which give rise to the vascular network, is mediated through VEGF/VEGFR activation of the signal transduction pathways. Thus blocking VEGF is an efficient strategy for blocking tumor angiogenesis. Several anti-VEGF drugs have been dev...
Rehana Shahida1, Tasnim Farasat1, Shagufta Naz1,* and Shahjahan2
...assessed as a measure of vascular damage. Different demographic parameters as age, BMI, waist /hip ratio, B.P., personal history and socioeconomic status were recorded. Fasting glucose and HbA1c was done by chemistry analyzer. Fasting serum insulin, IL-6, TNF-α and thrombomodulin levels were assessed by ELIZA. Gene expression was measured by RT-PCR. Insulin resistance was calculated by HOMA-IR. TNF-α and IL-6 levels were high in IGT and diabetic gr...
Bian Xunguang1,2, Li Jiancheng1, Xu Chu1 and Yang Li2,3,4,*
...l epithelium, glands and vascular epithelial cells. This study revealed the molecular expression of AR and the distribution of intracellular proteins in the oviduct of the hen, which provides an important basis for the regulation of the physiological activities of poultry oviduct and the molecular mechanism of sperm storage.
...
Abd El-Nasser Ahmed Mohammed*
...dicated presence of a neovascular capillary network around transplanted ovarian tissues. In addition, visible antral follicles and corpora lutea was demonstrated on the ovarian tissues upon transplantation. Histological examination indicated that transplanted young ovarian tissues restored function better than elder ones. It could be concluded that unilateral ovarian transplantation partially restored their developmental competence for producing ova. Such resu...
Sana Qanber Abbasi1*, Ejaz Ahmed2 and Rabia Sattar1
...pro BNP levels and Cardiovascular pathologies especially those involving left ventricular dysfunction which may depict a probable association between migraine and CVD. To compare the levels of serum pro Brain natriuretic peptide (pro BNP) between migraineurs and hypertensive migraineurs. It was a cross sectional comparative study in which serumpro BNP levels were measured in migraine patients and hypertensive patients with migraine. A blood sample of 3 cc was ...
Muhammad Kashif Maan1, Muhammad Arif Khan1, Shehla Gul Bokhari1, Muhammad Ijaz2, Hamid Akbar1, Sajid Umar 3 and Muhammad Luqman Sohail4,*
...um biochemical and cardiovascular effects of total intravenous anesthesia, xylzine-ketamine and inhalation anesthesia, isoflurane was clinically compared in healthy female rabbits (n=16) undergoing ovariohysterectomy. One group of 8 rabbits was anesthetized with combination of xylazine (3mg/kg) and ketamine (10mg/kg, I/V), while the second group (n=8) was pre-anesthetized with xylazine, followed by treatment with isoflurane (4%) with oxygen flow rate of 1L/min...
Kaleem Ullah1, Zafar Niaz2, Sami Ullah Mumtaz3, Sajid Abaidullah4*
...disease (COPD) and cardiovascular diseases strongly exists as diastolic dysfunction is commonly reported in COPD patients.
Objective: This study was conducted to determine the presence of left ventricular diastolic dysfunction in patients of COPD.
Material and Methods: A cross sectional study was conducted in Mayo Hospital Lahore for one year. A total of 50 confirmed cases of COPD were included in the study. History of smo...
G. Venkatesan* and Amit Kumar
... or host specific namely vascular endothelial growth factor (VEGF-E) and viral IL-10 genes. ORFV can cause high morbidity in adults along with considerable mortality in young suckling animals and showing an expanding host range even to marine species make this contagious virus, an important animal pathogen globally. Being zoonotic and endemic in most parts of the developing world, it is necessary to prevent and control the infection using latest molecular diag...
Iqra Arooj1,* and Shahida Hasnain2
...tively).
... 
Tahira Jamil*1, Mohammad Asghar1, Fatma Husain1, Haq Nawaz Bhatti2
...he development of cardio vascular diseases. Lovastatin is formed as secondary metabolic intermediate initiated by anion moiety (acetate) through polyketide chain reactions. The current work was put away to investigate the potency of Pleurotus strains for statin formation by cultivating them on lignocellulosic substrates (wheat straw, rice straw, banana stalk) in SSF for 8 days. Among Pleurotus species (P. nebrodensis, P. sepidus,
Akshay Sharma*, Mohit Mahajan, Madhumeet Singh and Pravesh Kumar
...y was done to assess the vascularity and functional activity of corpus luteum present on the left ovary. Ultrasonography was employed at weekly interval to judge the viability of embryo (up to 42 days), fetus (after 42 days) and late embryonic mortality, if any. Sexing of the twins was done on 56th and 70th day post artificial insemination and two male twins were confirmed on the basis of genital tubercle, median raphe, scrotal and penis impression. With the a...
Syeda Ain-ul-Batool1, Sadia1, Kathrin Blasius2,3,4, Angela Kaindl2,3,4 and Ghazanfar Ali1,*
...schsprung disease, cardiovascular and liver disorders. So far 21 genes are reported that cause BBS (BBS1-BBS21). A consanguineous family having clinical symptoms of BBS9 is described in current study. Mutation was detected in BBS9 on chromosome 7p14.3 using whole exome sequencing (WES). A splice acceptor site mutation (c.1131G>A) in exon 3 was revealed by Sanger sequencing.
...
Chaman Ara1*, Asmatullah1, Zainab Riaz1, Memoona1, Asma Chaudhary2, Shagufta Andleeb2
...erulosclerosis, abnormal vascular pole in liver and kidney respectively. But when turmeric powder was coadministered with BP, these damages were reversed to a great extent. So, this study has proved the protective role of turmeric against toxicity induced by BP in female albino mice.
Novelty Statement | Curcumin, an active component of turmeric along with its proven anti-fungal and antimicrobial activities also detoxify Pa...
Syeda Naila, Muhammad Ibrar, Fazal Hadi* and Muhammad Nauman Khan
...by mesophyll region with vascular bundle and the lower epidermis. The leaf features showed that palisade ratio was (7.35), vein islets number (9), and vein termination number (9.1), stomata number (47) and stomatal index were (42.72). Transverse section of the root showed outer epidermal cells, cortex and pericycle, xylem and phloem cells. Powder drug microscopy, ash analysis, extractive values and fluorescence analysis were also studied. Preliminary phytochem...
Ghulam Akbar1*, Muhammad Anjum Zia1, Ali Ahmad2, Neha Arooj1 and Shahneela Nusrat1
...t-align: justify;">Cardiovascular diseases are the leading cause of death along the world about 30% of all deaths occur due to cardiovascular diseases. Among fibrinolytic enzymes streptokinase (SK) is commonly used in the world to cure heart diseases because its low cost and efficacy. It’s a microbial origin enzyme produced especially by Streptococcus bacterial spp. Therefore, it is antigenic in nature due to microbial...
MA Liman1, QI Yongxiao1, Wang Wenji2* and Zhong Qianyi3*
...were studied to evaluate vascular development defects. G-Rh2 treatment up to 84.85 μM did not induce morphological defects in zebrafish. We observed suppression effect of angiogenesis by G-Rh2 in inhibiting intersegmental vessel formation from 30 to 84.85 μM in a dose-dependent manner. Moreover, quantitative real-time PCR revealed that G-Rh2 suppressed vascular endothelial growth factor (vegf) mRNA expression bu...
Turgay ĹžiĹźman1,*, Muhammet ÇaÄźrı Keskin1, Hatice Dane1, Ĺžeymanur Adil1, Fatime GeyikoÄźlu1, Suat Çolak2 and Esra Canpolat1
...neration and heterogenic vascular construction originating from congestion, deformation and dilatation. In kidney, degeneration, congestion, dilatation, and necrosis in proximal and distal tubules were recorded; moreover, expansions of Bowman’s space, infiltrations of lymphocytes, and glomerulonephritis were observed. Also, the frequency of nuclear abnormalities in erythrocytes showed significant differences between the sites. Quantitative analyzes of hi...
Xuya Zhou1, Ying Liu1, Deqin Xu1, Jie Bao1, Yaru Cao2 and Yong Jin3*
...crease the risk of cardiovascular disease, such as thiazolidine diketone: rosiglitazone, selective cyclooxygenase (COX)-2 inhibitors: rofecoxib, celecoxib. This study was aimed to find out whether unification of two drugs would increase cardiovascular side effects. Type 2 diabetic rat model was induced through feeding with fodder containing high sugar and lipid and intraperitoneal injection of streptozotocin. The adjuvant-in...
Ahmad Sadiq1, Muzafar Shah2*, Habib Ullah1, Irfan Ali1, Amir Alam3,
Navid Jalil1 and Muhammad Khan3
... the main cause of cardiovascular diseases (CVD). The present work revealed the role of glycated hemoglobin (HbA1c) for the detection of lipid profile and CVD. In recent study 108 (56 males and 52 female) type 2 diabetes (T2DM) subjects were diagnosed at Hayatabad Medical Complex (HMC) Peshawar and private diabetic clinic “Khattak Medical Centre” (KMC), Dabgari Garden Peshawar, Khyber Pakhtunkhwa, Pakistan. The normal or control group consists of t...
A. B. Badr1 ; M. A. S. El-kady2; and Kh. E. A. Saker2
...ghtly reduced. Moreover, vascular tissues lost their
normal shape and arrangement as xylem arms. The most interesting finding, lengths
of both , protoxylem and metaxylem were reduced while their widths were increased.
Ultrathin sections of symptomatic leaf tissue showed several cytological changes
characteristic of Potyviruses. The thlakoidal structure of the chloroplastes becomes
disorganized, abnorm...
Amel, S.M. Abo-Senna1; M.A. Nasr-Eldin2; B.A. Othman3 and A.A. Megahed4
...tion, and deformation of vascular bundles. The effect of late ZYMV infection decreased fresh weight and yield of squash plants....
Roheela Yasmeen1*, Nida Mobeen1 and Samia Chaudhry2
...reason for serious cardiovascular disease including myocardial injury. This virus can persuade cardiac damage, arrhythmias, severe coronary syndrome and venous thromboembolic complications. Patients of COVID-19 having already cardiovascular problems showed severe symptoms of this disease and have greater chance of death. This review article especially pays attention on cardiovascular sympt...
Ahmed K. El-Attar1, Samah A. Mokbel1 and Om-Hashem M. EL-Banna2
... necrosis in the zone of vascular cells. On the basis of mechanical
transmission, symptoms induced were similar to those caused by AMV. Presence of AMV in
basil plant was further confirmed by the results obtained from the laboratory-based techniques
such as (DAS)-ELISA, and RT-PCR using a pair of primers specific to the AMV-CP gene.
Phylogenetic analysis results indicated that AMV-Egypt that isolated from Basil i...
Samah A. Mokbel, Eman A. Ahmed, Hanan F. El-Kammar, Ahmed A. Kheder
... height and width of the vascular bundle.
Results: Phylogenetic analysis results indicated that SEA-CMV-isolate under study (acc. no.
MT491996) closely related (99.9%) to Beet-EG-CMV-isolate (JX826591), isolated from sugar beet
plants from Kafr El-Sheikh governorate, Egypt during 2012. Results of sequence analysis confirmed
the classification of isolate SEA as a member of group IA. Infection of sugar beet leaves ...
Kanwal Haneef1,2, Rakhshinda Habib1,3, Nadia Naeem1,3 and Asmat Salim1,*
...font-size: small;">Cardiovascular disorders are major cause of death globally. Regeneration of cardiac tissue with the use of stem cells has appeared as an effective cell-based therapeutic option. Mesenchymal stem cells (MSCs) are the potential candidates for cell therapy due to their ease of isolation, proliferation, anti-apoptotic and proangiogenic properties. MSCs have the ability to fuse with somatic cells in vivo and depending upon the microenviron...
Meiping Deng1, Xiaowen Ye1, Jiashan Wu1, Lijuan Chen1, Xiaoxia Jiang1, Changzheng Zhang1, Peiling Zhou1* and Yi Luo2*
...erns regarding the cardiovascular effects of arecoline treatment in clinical practice.
...
Blood Profile of Soybean Meal Substitution with Black Soldier Fly Larvae in New Zealand White Rabbit
Ardi Prasetio1*, Christina Maria Sri Lestari2, Sutaryo Sutaryo2, Manar Fayiz Mousa Atoum3,4, Muhammad Zahoor5, Asma Nisar6 and Muhannad Illayan Massadeh7
...an lead to several cardiovascular diseases. Rabbits (Oryctolagus cuniculus Linnaeus, 1758), known as low cholesterol meat, can be alternatively chosen for daily consumption. Soybean meal (SBM), as the primary protein source in rabbit ration, has some disadvantages. Protein value in Black Soldier Fly Larvae -BSFL (Hermetia illucens Linnaeus, 1758) is equal to SBM and better in the amino acid profile. However, the chitin contained in BSLF may cause...
Juliet N. Ozioko1, Obinna V. Ayogu2, Benjamin O. Ezema1, Dilibe C. Uramah3 and Kingsley O. Omeje*,1
...ndex implicated in cardiovascular ailments was lowered after consumption of the leaf extract of C. albidum. The liver marker enzymes aspartate transaminase and alanine transaminase showed no significant changes in their serum activity. Similarly, superoxide dismutase and catalase showed no significant increase after the period of study....
Hong Liu and Rui Xu*
...easurement of the 3D-CPA vascularization index (VI) and flow index (FI) of the fetal kidney and the vascularization flow index (VFI) in the early pregnancy. In addition, blood flow parameters of the uterine artery and fetal umbilical artery of the pregnant woman were correlated at the 12th week and the 22nd week. We found that FI, VI and VFI decreased in the mild and severe prehypertension groups were compared with the contr...
Rafiqul Islam1, Nasrin Sultana1*, Md. Abu Hadi Noor Ali Khan2
...ure can harm adult cardiovascular health. Dexamethasone (DEX) is a widely administered synthetic glucocorticoid. The focus of this study was determining how DEX affects serum biochemistry (cholesterol and triglycerides), morphology, and morphometry of broiler hearts. Eighty one-day-old chicks (DOCs) were randomly categorized into four groups i.e., one control group and three trial groups (i.e., E1, E2, and E3). The control group was given commercial broiler fe...
Feng Xu, Weijing Fan and Guobin Liu*
... rutin on ox-LDL-induced vascular endothelial cell injury, and to analyze whether the mechanism is related to the regulation ofNEXN-AS1 and miR-410-3p expression. The CCK-8 method was used to detect the toxicity of rutin of different concentrations (0, 25, 50, 100, 200, 400 μmol/L) on human umbilical vein endothelial cells (HUVECs). HUVECs were treated with 100 mg/L ox-LDL for 24 h for establishing HUVECs injury model, and then treated with rutin in differe...
Tao Ren1, Guiqiu Cao2, Xiao Han3, Feng Tan1, Qiaoli Chen4, Shicheng Yang5 and Haiyan Zhang6*
... a common multiple cardiovascular disease (CVD) in clinical settings. It is a major contributor to mortality and morbidity worldwide and causes a serious threat to human life and health. Naringenin, a flavonoid possesses the potent antioxidant potential and it is proposed to be useful in the treatment of CVD. In this experimental study, we aimed to scrutinize the cardio-protective effect of naringenin against the I/R induced myocardial injury and elucidate the...
Chinar Mustafa Mohammed1*, Thamer M. Bashir1, Omar A.M. Al-Habib2, Farhad Ramadhan1, Mohammed Bassam1
...e, on behavior and cardiovascular function in the male rat following arrhythmia induced by the social stressor. Here, we studied levels of heart electrical activity following experimental conditions: Cage control, social isolation in standard rat housing for 14 days, and pharmacokinetics effect of intravenous administration of different doses of taurine on arrhythmia induced by social isolation in vivo after. The ECG signals and parameters were recorded and an...
Mohamed Lebdah1, Sahar Abd El Rahman2*, Ahmed Attia3, Reham Karam2, Naglaa Fathy Saeed Awad1, Mohamed Ibrahim El Bagoury1
...rative encephalitis, perivascular cuffing, congestion of hepatic sinusoids, degenerative changes in the hepatic cells and interstitial lymphocytic aggregations in the liver and focal pneumonic areas in the lung. Pooled samples from the investigated quails were inoculated in specific pathogen free embryonated chicken eggs (SPF-ECEs). The dead embryos showed hemorrhages, congestion and dwarfism. The collected allantoic fluids were examined later by haemagglutina...
Muneeza Zafar1,2,3, Fazli Rabbi Awan2,*, Munazza Raza Mirza3,*, Sumaira Nishat2,4, Sajid Ali Rajput5 and Imran Riaz Malik1,*
...udies in cohort of cardiovascular patients. While their structural impact on APOB may suggest these predicted nsSNPs possibly be a better drug target and contribute to the treatment and better understanding of human cardiovascular disease....
Zahra Hussain, Zulfiqar Ali* and Rida Ahmad
...al issues 17%, and cardiovascular issues 7%. In animals, out of total 102 different diseases and pathological conditions, the maximum variation was noted in mouflon sheep (Ovis orientalis orientalis), hog deer (Axis porcinus) and spotted deer (Axis axis). In birds, 37% infectious diseases, 24% generalized conditions, 15% gastrointestinal and 9% respiratory issues were recorded. Among infectious diseases, salmonellosis, infectious coryza and colibacillosis were...
Xiaojing Liu and Zhongxin Li*
...nd analyze its action on vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMP-) 9 protein expression in kidney tissues, in order to reveal the mechanism of TSG. After 12 weeks of administration, compared with those in the DN modeling group, 24 h urine protein, serum creatinine (Scr), blood urea nitrogen (BUN), blood uric acid (UA), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) significantly reduced in rats treated w...
Muhammad Kashif Iqbal1*, Khalid Mehmood2,4, Shakeel Ahmed3, Fazul Nabi4, Muhammad Arif Rizwan1, Muhammad Kaleem1, Mushtaq Ahmed1, Abdul Waheed1 and Jiakui Li5
...haracterized by enlarge avascular growth plate with lesions in proximal tibiotarsal bone. The aim of present study was to investigate the antioxidant capacity of FK228 and role of vascular endothelial growth factor (VEGF) and Flk-1 genes in thiram induced TD. One hundred and fifty broiler chicks were equally divided into 3 groups: control; thiram fed; and FK228 treatment group. Expressions of VEGF and Flk-1 genes were analyz...
Muhammad Akram1*, Muhammad Imtiaz Shafiq2, Amber Malik3, Farmanullah Khan4, Munir Ahmad Bhinder5 and Muhammad Sajjad6
...t-align: justify;">Cardiovascular diseases (CVDs) are major health problems all over the world. Oxidative stress contributes an important pathological role in the development of CVDs. To counter this oxidative stress, the most important natural antioxidant defense mechanisms include endogenous glutathione concentration, superoxide dismutase, catalase, and glutathione S-transferase (GST). GST neutralizes reactive oxygen species to regulate physical homeostasis ...
Aysam Fayed1, Mohga A Ibrahem2, Soha A. Hassan3, Mohammed Abdalla Hussein4*, Tamer Roshdy1
...e Type 2 diabetes, cardiovascular disease, and several types of cancer has made obesity a challenge for world health. The current study’s objective was to assess the antioxidant capacity of cranberry extract in high-fat diet-induced obesity. For eight weeks, 36 white albino rats weighing 197±10 g were selected at random to five groups: Group I was administered a regular diet; Group II was fed a high-fat diet; Group III was given a high-fat diet pl...
Xiaoli Yao1, Xiaofang Yue2, Yue Yang3 and Guobin Zhang3,*
...troban on the treatment, vascular endothelial function, inflammatory factors and neurological function in patient with acute cerebral infarction. A total of 80 patients with acute cerebral infarction were randomly divided into 2 groups each of 40 cases, regardless of gender, aged from 55-75 years, who underwent treatment in hospital from January 2018 to December 2020. Each group received routine treatment, in which the treatment group received LMWHC alongwith ...
Xiaoli Yao1, Xiaofang Yue2, Yue Yang3 and Guobin Zhang3,*
...troban on the treatment, vascular endothelial function, inflammatory factors and neurological function in patient with acute cerebral infarction. A total of 80 patients with acute cerebral infarction were randomly divided into 2 groups each of 40 cases, regardless of gender, aged from 55-75 years, who underwent treatment in hospital from January 2018 to December 2020. Each group received routine treatment, in which the treatment group received LMWHC alongwith ...
Ashira Manzoor1, Imran Ahmad Khan1,2*, Muqadas Sadiq3, Muhammad Omer Iqbal4 and Shaukat Hussain Munawar5
...r the treatment of cardiovascular disorders....
Samina Kausar1, Rana Badar Aziz2, Muhammad Waseem3, Muhammad Ahmad3, Hamza Shafiq4, Muhammad Asim5, Usama Zia6, Sobia Afzal7, Wanpeng Xi8*, Mansoor Hameed1* and Muhammad Usman Shoukat9
...ring the chance of cardiovascular illnesses or cancer. The tremendous results of carotenoids in human food have prompted numerous efforts in plant genetic engineering to supply products with greater carotenoid accumulation, which isn’t always only beneficial for agriculture but also has consequences for scientific research in terms of organic, chemical, and molecular or genetic regulation. Carotenoid metabolism and its regulatory network is not only incr...
Chattida Panprom1, Nakrob Pattanapon1, Wannisa Meepoo1, Soontaree Petchdee2*
...vents and preserve cardiovascular functions. This case report provides recommendations for anesthetic protocols and management in dogs with valvular heart disease. This study suggested that the anesthetic drug protocol of alfaxalone 2.5 mg/kg and a maintenance fluid rate of 5 mL/kg/hr in dogs with valve disease is safe and appropriate for preserving cardiovascular functions.
Keywords | Dog, General ane...
Sara Magdy Hashim1, Elshaimaa Ismael2, Mohamed Tarek3, Faten Fathy Mohammed1*, Fatma Amer Abdel Reheem3, Rawhia Esawy Doghaim1
...flammatory, necrotic and vascular reactions that involve different tissues. The immunohistochemical characterization of viral antigen revealed direct relation between viral residence in tissue and developed pathology. The present study confirmed that H5N8 HPAI clade 2.3.4.4b, became a predominant strain during the period 2018-2020, causing severe outbreaks in duck farms in Egypt.
Keywords | Avian influenza, HPAI, H5N8, Ducks, Pathology, Egypt.
Marwa S. Khattab1*, Ahmed H. Osman1, Huda O. AbuBakr2, Rehab A. Azouz3, Asmaa A. Azouz4, Heba S. Farag5
...yperplasia with mild perivascular mononuclear cells infiltration. Conclusion: Different levels of ivermectin residue were detected in bovine skin samples collected from slaughterhouses in Egypt however the degree of damage caused by ectoparasites exceeds the damage caused by ivermectin.
Keywords | Ectoparasites, Ivermectin, Histopathology, Immunohistochemistry, Oxidative stress, Pesticides, Skin damage, Slaughterhouses.
...
Ghulam Akbar1*, Muhammad Anjum Zia1, Amer Jamil1 and Faiz Ahmad Joyia2
...ortality rate with cardiovascular diseases is 85% in less developed countries and 75% prevalence is in women. The wild and mutant strains of Streptococcus mutans were used for this trace element optimization study. There are some salts like KH2PO4, K2HPO4, NaHCO3, CaCO3, CH3COONa.3H2O and FeSO4. 7H2O have been optimized for the production of SK. The K2HPO4 has shown the highest enzymatic activity with UV-Et mutant 680.0 UmL-1 and with CaCO3 UV-Et mutant has be...
Mohamed M. Bahr1, Mohamed S. Amer1*, Khaled Abo-EL-Sooud2, Shaimaa M. Kamel3, Marwa A. Fouly4, Ahmed N. Abdallah5, Ashraf A. Shamaa1, Omar S. El-Tookhy1
...pithelial hemorrhage and vascularization. These findings prove that EVs have the ability to heal corneal wounds even if in the peripheral parts of the cornea that are deficient in limbal stem cells. Conclusion: In terms of safety, quality, regulatory concerns, and cost, EVs are superior to corneal transplantation and live stem cell therapy.
Keywords | Mesenchymal-stem-cell, Xeno-Exosomes, corneal-ulcer, histopathology, corneal-transplantation, AS-OCT, ...
Mian Shamas Murtaza1,*, Aysha Sameen2, Saima Rafique3, Muhammad Shahbaz1,*, Nabeela Gulzar4, Mian Anjum Murtaza5, Umar Farooq1 and Iram Hafiz6
...rtension, obesity, cardiovascular diseases etc. Inulin is a food ingredient that belongs to a class of carbohydrates known as fructans with degree of polymerization range from 2-70. Resistant starch is obtained by chemical and enzymatic treatment of starch to increase its properties. These have functional and health-promoting properties as they reduce caloric value, add dietary fiber and endorse prebiotic effects. These are frequently used in industrially proc...
Monu Karki, Amit Kumar and Gnanavel Venkatesan*
...ients and oxygen supply (vascular endothelial growth factor), ORFV possesses several unique strategies, to fight against host immune environment. Some of the genes have been acquired from the host and some are flowing through the family and genus evolving with the virus to adapt and efficiently set up an infection in immune-loaded host cells. This review focuses on the important virulence genes of the orf virus and their functions with recent advances and the ...
Cuiping Liu
...d Irisin, and inhibiting vascular calcification....
R. Singh1† and R. Z. Sayyed2
...edullary and
vascular regions was observed by positively dark stained nucleoli, nucleoplasm and cytoplasm of their cells and
syncytium. High DNA amount was observed in concentrate form in infected cells of cortex, pericycle and xylem
tracheid of vascular region. Hyper hydrolysis of starch induced by M. incognita in sponge gourd roots was tested by
studying the localization of a...
O.S. Osunlola† and B. Fawole1
...t cortex, endodermis and vascular cells. Female nematode
displaced root cells and occupied large cavities and the surrounding cells were compressed. The nematode induced
formation of an average of four giant cells each with 7 ± 0.5 nuclei around the head of nematode close to vascular
cells. Nematode eggs were seen in the cortical cells but more eggs were...
N. Hajra, F. Shahina1, †, K. Firoza1 and R. Maria
...s observed in T2 and T5, vascular
tissue obliterated by root-knot nematodes. However, VAM fungi suppressed the effects of root-knot nematodes in
T4. Giant cells, egg-masses and females of nematodes were observed in T2, T5 and to some extent in T3. VAM fungi
spores were seen in cortical as well as in pith region of root in T3.
...
Zongliang Li1, Rongxin Ma2,*, Yan Wei1 and Jianghua Zuo3
...l maleate on circulating vascular endothelial growth factor and basic fibroblast growth factor in children with cutaneous hemangioma. Eighty children with hemangioma treated in the Provincial Women and Children’s Hospital from May 2018 to April 2019 were enrolled in the study, including 37 males and 43 females. The children were randomized into two groups according to the experiment: the conventional treatment group (taking one tablet of propranolol) and...
MUHAMMAD MUNEEB SOHAIL1, FATIMA AMEER2, GUR CHARN SINGH2, MUHAMMAD ZAID1*
...diabetes mellitus, cardiovascular disease (CVD), cancer, or anemia were excluded from this study. Statistically significant and non-significant results were obtained for different lipoprotein fractions. Although, Body Mass Index (BMI) was a good classical indicator of obesity, other indicators like A Body Shape Index (ABSI) and Body Roundness Index (BRI), also proved significant in assessing the type and severity of dyslipidemia. Different lipoprotein fraction...
Pengliang Xie1, Lufang Zheng2*, Mingxia Dong3, Huaiqiang Zhang1 and Fang Chen1
...the mechanism of soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) and sVEGFR-2 in regulating branch retinal vein occlusion with macular edema. A total of 45 patients with branch retinal vein occlusion and macular edema who were treated at Tangshan Eye Hospital from November 2018 to June 2020 were enrolled in the study, including 19 cases of localized macular edema, 12 cases of diffuse macular edema, and 14 cases of cystoid macular edema. Forty-...
Umara Amir ud Din1, Waqas Ahmed Khan1*, Khurrum Shahzad1,2, Basharat Ali3, Misbah Hussain1,4 and Fazli Rabbi Awan4
...olism, vasoconstriction, vascular tone and renal hemodynamics. Angiotensin converting enzyme (ACE) is a key member of RAAS pathway and target for anti-hypertensive drugs. ACE (I/D) polymorphism studies for its association with kidney function and risks of DN have been reported in different populations but with varying results. Hence, the objective of current study was to study the association of ACE (I/D) polymorphism with risk of DN in Pakistani subjects. For...
Amr N. El-Shahat1*, A.M. Abdul Azeem1 and Mohamed H.M. Abd el Megid2
... and prevention of cardiovascular diseases. The present study aims to investigate the effectiveness of bay leaf extract (BLE) in protection against high cholesterol diet (HCD) induced hypercholesterolemia. About thirteen compounds of essential oils were identified by GC/MS analysis including 1.8-cineole, Linalool and sabinene which represent the main volatile oils of bay leaf. Supplementation of BLE with HCD for 10 weeks resulted in reduction in the levels of ...
You-Ming Teng, Wen-Zhou Liu and Li Yang*
...pertrophy induced by renovascular hypertension were given a gavage of pioglitazone 5–10 mg/kg for 4 weeks. Our crew determined systolic blood pressure (SBP) and diastolic blood pressure (DBP). Heart mass index (HMI), left ventricular mass index (LVMI), myocardial cell diameter (MCD) and surface area (SA) were further estimated. We members determined FFA and Ang II levels. HE and Masson staining were estimated histopathological changes. The protein and mR...
Atef M. El-Sagheer1*, Aline F. Barros2, El-Sayed M. Abd El-Aal3, Mohamed M. Gad4, Doaa S. Mahmoud4 and Amr M. El-Marzoky3
...ing site extended to the vascular cylinder. In roots infested with M. incognita only, the laceration of the feeding site in the inner cortical tissue and spread to the vascular cylinder were selected as the initial feeding site, as shown. Multinucleate cells, giant cells, and thickening of cell walls were also associated with this penetration. The cytoplasmic globules as phenolic and lignified structures were shown to be ass...
Xiaowei Huang, Yajie Wang, Jia Zhou, Junxiu Liu, Zhe Lin and Ruili Li*
...tic function and improve vascular endothelial injury in AA model rats by regulating TLR4/NF-κB signaling pathway....
Asifa Majeed*, Amir Rashid, Palvasha Waheed, Asma Faryal, Aden Razaq and Ayesha Maryam
...factors to develop cardiovascular diseases. The genetic predisposition in association with environmental and lifestyle modifications can play a central role in the progression of diabetic dyslipidemia. A cross-sectional study was designed to detect pathogenic genetic variants in APOA1 and ABCG1 genes associated with dyslipidemia in type 2 diabetic patients. A total of ninety subjects of both genders, aged between 30-70 years were randomly selected and fu...
Haiyan Nan, Ran Feng, Guiling Zhang and Jingqin Liu*
...dings of lower extremity vascular disease and plaque formation and the formation of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM). In this study recorded patients who were admitted to the No.1 hospital of Baoding from August 2017 to January 2020. We continuously observed the comprehensive diabetes complications screening or blood glucose of 517 hospitalized patients with T2DM. 67 subjects were excluded due to incomplete physical exam...
Wenxiao Jia1*, Yilinuer Yilihamu1, Yunling Wang1, Shuang Ding1, Dilinuerkezi Aihemaiti1, Hanjiaerbieke Kukun1 and Yanhui Ning2
...lly thickened, while the vascular wall of the abdominal aorta in the control group exhibited no abnormality. The intima of the abdominal aorta in the experimental group showed pathological manifestations of unstable atherosclerotic plaque, while that in the control group exhibited no abnormality. This method of modelling is simple to conduct, has a high success rate and requires a short duration, making it an effective animal model of unstable atherosclerotic ...
Jasir Hakim Hidayah1,2, Yos Adi Prakoso2, Sitarina Widyarini3*
...ary haemorrhage, and perivascular oedema compared to the others. This study proved that calabash can be an alternative therapy against ischemic stroke. In advance, the experimental intoxication of this fruit and its processing product must be elucidated. ...
Yanmei Wang1,2, Haoyun Li1, Lijuan Han1 and Wenkui Wang1*
... caused pulmonary artery vascular remodeling, and lead to PH. This study aims to provide theoretical basis for finding new therapeutic targets for broiler PH....
Danish Kamal2, Muhammad Abbass Khan1, Ghulam Mujtaba-Shah1, Naveed Ahmed1, Maryam Iqbal¹, Basharat Hussain Shah1 and Imtiaz Ahmed1*
...s, mesophyll tissues and vascular bundles. Stomatal index of different tea varieties and clones was array from 33.9 to 45.4 respectively. Highest was mentioned in clone P-7 because high number of stomata found in lower epidermis....
Anas M. S. Al-Haj Afandi*, Ahmed H. F. AL-Bayati
...on site revealed that neovascularization was distributed in group (B) more than that in group (A) while, the deposition of fibrous connective tissue in group (A) treatment group was denser than that in group (B). Highly incorporation between the sheet and surrounding tissue was observed in group (A) more than that in group (B). At the same time, the macroscopic changes in the caprine acellular dermal matrix treatment group included decreasing the thickness of ...
Abdul Aziz1,2, Hamad Bin Rashid1*, Muhammad Arif Khan1, Asim Khalid Mahmood1, Ayesha Hassan1, Hamid Akbar1, Sadaf Imran1, Naveed Hussain1, Muhammad Umar1, Muhammad Asif1, Sajjad Javaid1 and Mamoona Chaudhry3
...align: justify;">Stromal vascular fraction (SVF) has become a promising candidate for regenerative therapy. SVF is preferred over culture-expanded stem cells due to its quick availability for clinical use and easy preparation. Burn wounds are a serious problem faced by veterinary clinicians in various animals. In this regard, the study was planned for the preparation and characterization of SVF from the adipose tissue of rabbits. Twelve healthy rabbits having ...
Mohammed A. Ali1*, Firas A. Alhasson1, Thaer A. Mohsin2
... matrix. The retina was avascular, and the layers of the retina were arranged in a normal vertebrate pattern. ...
M. Osman1, Kh. El-Dougdoug2, E. T. Abd El-Salam3, R.M. Taha4 and R.M. El-Hamidl
... spongy cells as well as vascular elements of the midrib formed in two patches. The upper patch was completely divided in two parts. Scanning electron microscopy showed alteration in epidermal cells elongated, deformed, and disconnect hairs. decrease of opened stomata, destroyed and forming giant cells. The midrib cells of infected leaves showing clear elongations as well as deformation. Transmission electron microscopy illustrated highly thickened with clear ...
Muhammad Talha Sajjad1, Hamid Akbar1*, Muhammad Arif Khan1, Muhammad Hassan Mushtaq3, Shehla Gul Bokhari1, Muhammad Abid Hayat4 and Ghulam Mustafa2
...right region of back. Neovascularization was assessed on days 14 and 28 by color Doppler ultrasonography and cytokeratin staining. Wound re-epithelialization and the number of fibroblasts were assessed by cytokeratin staining. All data were statistically analyzed. We observed that PRP-wounds had highly significantly (P<0.01) increased levels of neovascularization on days 14 and 28 than control wounds. PRP-wounds had highl...
Rehana Shahida1, Shagufta Naz1*, Tasnim Farasat1, Saima Sharif1, Shah Jahan2 and Farkhanda Manzoor1
...of atherosclerotic cardiovascular disease. The development and outcome of atherosclerosis are both influenced by vascular inflammation. The main purpose of this study is to find the impact of Interleukin-6 (IL-6) and thrombomodulin on vascular damage in the patients having impaired glucose tolerance (IGT) and to identify the relationship of IL-6 with insulin resistance. The patients visiti...
Taghreed Jabbar Humadai*, Bushra Ibrahim AL-Kaisei
...ells infiltration in the vascular connective tissue, fibrovascular tissue with newly form capillaries between epididymal tubules. The Immunohistochemistry study revealed an increase in the scoring of interleukin1 (IL1) expression in testes and epididymisthat showed the highest score (3), whereas the tumor necrosis factor alpha (TNF α) expression showed highest score (4) in the testes and epididymis tissue. The conclusi...
Iqra Munir*, Farrah Iftikhar, Hira Fatima, Sunbal Khalil Chaudhari and Roha Ramash
...lants used to cure cardiovascular diseases and ulcers. The purpose of this study is to recognize wild plants gathered for medicinal purposes by the local residents of Mandi Bahauddin and to document the common names and therapeutic uses associated with these plants....
Marah Salim Hameed1, Ali Ibrahim Ali Al-Ezzy2*
...renal blood vessels, perivascular cuffing, and infiltration of inflammatory cells in the dilated blood vessels. Congestion of glomerular capillaries. While (T3) revealed sever congestion of renal blood vessels, perivascular cuffing, and infiltration of inflammatory cells in the dilated blood vessels. Extensive distension of Bowman’s space with sever congestion of glomerular capillaries and extensive cellular swelling o...
Hayder S. Rwayyih*, Tahani S.S. Al-Azawi
...as a protection on cardiovascular system in menopause estrogen deficiency and ovariectomized female rabbits. Alpha lipoic acid could fight the deleterious effect of menopause estrogen deficiency.
Keywords | Ovariectomy, Menopause, Estrogen deficiency Alpha lipoic acid, Cardiovascular system, Rabbits, Histology, Biological markers
... 
Murad Ali,SHAHID ALI,Bakhtiar Gul,Haroon Khan,SAJJAD ALI,KHAWJA JUNAID,KASHIF ALI,FIDA HUSSAIN
Sri Purwanti1*, Wempie Pakiding1, Marhamah Nadir1, Nurhayu2, Kusumandari Indah Prahesti1, Sitti Nurani Sirajuddin1, Jasmal Ahmari Syamsu1,4, Andi Mushawwir3
...f which affect the cardiovascular function and energy metabolism in chickens. This research aims to determine the value of lipid regulation and cardiovascular biomarkers of native chickens given a combination of maggot, indigofera and turmeric. A total of 120, 4-week-old male indigenous native chickens with an average initial weight of 42-45 g were divided into 3 treatment groups and fed diets, namely P0 (basal feed), P1 (ba...
Kingsley O. Omeje1, Juliet N. Ozioko2, Amaechi L. Ogara2, Benjamin O. Ezema2* and Dilibe C. Urama3
...pose the animal to cardiovascular diseases....
M. Ayaz and G. M. Nasir
...heids, procumbent cells, vascular tracheids, pits on
vascular tracheids and pit pores. On the basis of these
anatomical variations a key is prepared for the
identification of important conifers of Pakistan....
Charles D. Bonham, Javed Ahmed and Larry L. Larson
...titative measurements of vascular plant species and
the physical attributes of the site. Data analyses
included principal component, McNaughton and Wolf's
niche index, and discriminate and canonical analyses.
The analyses techniques identified under story
sensitivity to aspect, elevation, and soil profile
attributes that influence soil moisture. The under story species studied exhibited a relative independence to
over story composition and dominance....
Sura Ayed Radam*, Inam Badr Falih
...rplasia with obvious perivascular Mono Nuclear Cells MNCs aggregation composed of lymphocyte and macrophage mainly in hepatic tissue of 3rd group with evidence of reactive lymphoid hyperplasia in splenic tissue of 2nd group and periarteriolar, pericortical lymphoid hyperplasia were reported in spleen of 1st group immunized with Streptococcus pyogenes lyophilized antigen. Conclusion This study provide we can conclude that jointly of concanavalin-A and S.pyogene...
Ghodrat Akhavan Akbari1, Saman Hayadokht1, Saeed Sadeghiyeh Ahari2 and Ahmad Gasi1*
...time and worsening cardiovascular system is important and necessary. The main objective of the present study was to evaluate the efficiency of Meperidine and Oxycodone in preventing shivering in patients who underwent inguinal hernia repair with spinal anesthesia. The present study consisted of patients with herniorrhaphy in the Fatemi and Imam Hospital of Ardabil who were studied through a double-blind clinical trial. with spinal anesthesia from 2017 through ...
Yugang Meng1*, Xiting Yan2 and Haiying Liang3
...n on the levels of serum vascular endothelial growth factor (VEGF), anti-endometrial antibody (EMAb) and sex hormone in patients with endometriosis. Participants in the study, 92 patients with endometriosis admitted from June 2016 to May 2017 to our hospital, randomly were divided into control group and study group (46 cases in each group). The control group was given routine treatment such as medroxyprogesterone acetate tablet, and the study group was given i...
Muhammad Farooq* and Sanam Zarif
...y 700 foreign species of vascular plants that are found in Pakistan. These include high-impact invaders such as Broussonetia papyrifera, Prosopis juliflora, Parthenium hysterophorus, and Lantana camara. In Pakistan, invasive plants have significant negative effects on ecosystems and local flora displacement. For instance, the allelopathic effects of Eucalyptus camaldulensis have adversely affected the growth of grass and bushes in the Malakand highlands. In or...
Roy Sukbir Singh1, Jekson Martiar Siahaan2,3*, Endy Juli Anto4, Syafruddin Ilyas5, Putri Eyanoer6, Hendrika Andriani7,8
...at is connected to cardiovascular events. It is characterized by disruptions in lipid profiles and is frequently accompanied by endothelial dysfunction, oxidative stress, and inflammation. Aloe vera, renowned for its secondary metabolites, is suggested as a potential treatment because of its hypolipidemic, antioxidant, and anti-inflammatory qualities. This study employed both in-silico and in-vivo approaches to explore these effects. The in-silico analysis inv...
Mehak Muhammad Ashfaq1*, Aqsa Naeem Chawla1, Muhammad Umaid Ali1 and Adnan Ahmed Bhutto2
...er risk of cancer, cardiovascular disease (CVD), and other neurological conditions, including Alzheimer’s, Parkinson’s, and others. Nevertheless, due to research constraints and confounding variables such as study design, population size, and usage of various chocolate product types, dosages, and contents, additional large-scale human experiments are required to validate and advocate the chocolate diet. An increasing amount of research shows the be...
Emad M. Gad1, Haidy G. Abdel-Rahman2, Mohy Eldin Abd-El-Fattah1, Merna M. Kamal1, Ahmed Shaker Eltahan3, Amina A. Dessouki3*
...so rated as a major microvascular complication of diabetes mellitus. The prevalence of diabetic nephropathy is more than 40% of diabetic patients. Even with current treatments, many individuals with DN progress to end-stage renal disease and needing dialysis or kidney transplantation. So,the development of new prevention and treatment strategies of diabetic nephropathy is required. The existent study looked at the impact of dapagliflozin, mulberry fruit and le...
Rawya Shakir Mohammed*, Baraa Najim Al-Okaily
...ating the disturbance of vascular endothelial growth factor (VEGF) mRNA expression, histomorphometric and histological alterations of ovaries in healthy rats that administered doxorubicin.Thirty-two fully grown female rats were randomly divided into four equal groups and were treated for two weeks as follows: The control group (C) of rats were administered distilled water orally ; Group G1: Rats in the this group had injected intraperitoneal of doxorubicin (4....
Adel Sobhy1, Ahmed El-khamary1, Ahmed M. Rashwan2,3, Ashraf Shamaa4, Mostafa Kassem5, Mohamed M. A. Abumandour6*, Ahmed El-Mansi7, 8 and Ahmed G. Nomir2
...re efficient and avoided vascular penetration than site p2....
Eman Wahsh1, Tarek M Ibrahim2, Mirna E. ElAwady3*
...ng properties. The cardiovascular drugs, calcium channel-blocker (CCB), nifedipine, and beta-blocker, propranolol, are currently investigated for their possible anxiolytic effects. Anxiolytic properties of CCBs are attributed to inhibition of brain calcium transportation. Propranolol reduces the physical signs of anxiety by blocking adrenergic neurotransmitters. Currently, Vogel conflict paradigm was applied to measure anxiety and validated by using anxiolytic...
Nbaa Mutea Abid AL-Alh1, Nuha Hatem Khalaf1, Nagam Khudhair1*, Ahmed Khalid2
...sels congestion with perivascular inflammatory cells infiltration, bile ducts epithelial hyperplasia. we noticed that administration of ethanolic extract of Saussurea costus root and in resulted in amelioration of the morphological changes in Chlorpromazine treated rats, improved parameters and restored the parameters to near normal compared with group G1. The G5 group that was dosed with the alcoholic extract of the Indian Costus root and in conjunction with ...
Ashraf B. Said*, Ibrahim A. Ibrahim, Hoda I. Bahr, Marwa A. El-Beltagy
...leviating micro and macrovascular complications. Here, the current study conduct to investigate whether the efficacy of long-acting GLP-1 derivatives or Bone Marrow mesenchymal stem cells as a novel potential glucose-lowering therapy was comparable to metformin, the most often prescribed oral treatment for T2DM in male rats with STZ-induced T2DM.70 healthy male rats were divided into two groups one control (10 rats) fed with commercially available normal diet ...
Ma Huadan1,2,3, Sher Zaman Safi3*, Huang Junjie4*, Wei Hua5, Guo Xingrong6 and Ikram Shah Bin Ismail3
...l for maintaining normal vascular function. Studies have shown that MEG3 plays an important role in the regulation of VECs function, including the proliferation, migration, apoptosis, angiogenesis, and inflammatory response of VECs. This paper will review the effect of MEG3 on the function of VECs and its potential molecular mechanism, aiming to provide a conceptual basis for the potential of using MEG3 as a clinical diagnostic, prognostic, and targeted therap...
