Amtul Jamil Sami1,*, Sehrish Bilal1, Madeeha Khalid1, Muhammad Tahir Nazir1 and A.R. Shakoori2
... describes the effect of saponins, isolated from a medicinal plant Azadirachta indica on the CNS enzymes of a stored grain pest, Tribolium castaneum and a socioeconomic insect, Apis mellifera. A comparative study was designed to identify the role of saponins on insect acetylcholinesterase (AChEs). The enzyme activities were tested for the effect of saponins. The AChE a...
Sabi-Ur-Rehman1, Anwar Khalid2, Qazi Najam Us Saqib3, Farooq Ahmad1, Shaheed-Ur-Rehman4, Neelam Zaman3, Ayeza Mehmood5 and Abdul Samad6*
...xtracts as well as crude saponins isolated from leaves and roots of Sarcococca saligna, using disc diffusion method. The tested bacterial strains include, B. subtilis, E. coli, S. aureus, P. fluorescens and fungal strains were Aspergillus. niger, A. flavus, and D. turcica. The maximum zones of inhibition, 23.00±0.56 mm and 25.00±0.50 mm was given by ethyl acetate fraction of leaves against P. fluorescens and A. niger respectively. The crude
Muhammad Naeem Khan* and Asad Jan
...ds, phenols, flavonoids, saponins, tannins and sterols, however in n-hexane fraction (HxF) only flavonoids and saponins were detected. In quantitative analysis, among all the solvents, ethyl acetate fraction (EAF) had highest amount of phenol (27.4 mg/g), flavonoids (15.5 mg/g) and alkaloids (3.14 mg/g), while MCE displayed maximum amount of saponins (34.3 mg/g). In the proximate analysis,...
Gregory Ejikeme Odo1,*, Juliana Ekenma Agwu1, Nkechi Nweze2, Clara Ikegbunam2,Felicia Ekeh N1, Vincent Ejere1, Ngozi Ezenwaji1, Reginald Njokuocha2, Godwin Ngwu1 and Fabian Okafor1
...ac glycosides, steroids, saponins, and tannins are moderate in abundance (other constituents such as the cardiac glycosides, steroids, saponins, and tannins that were moderate in abundance (++). There was a dose duration dependent (p < 0.05) decrease in RBC in all the groups. There were also duration-dependent decrease in MCV values obtained in this research as against duration and dose dependent increases in MCH, and MCH...
Mahmoud Mohamed Ahmed Youssef* and Suzan Abd-Elazeim Hassabo
The Role of Genetic Engineering in Management of Plant Parasitic Nematodes with Emphasis on Root-Knot Nematodes: A Review
...ng gene (s) required for saponins production is effective in increasing crop yield together with fixing nitrogen. Escherchia coli is still used as a host for the recombinant DNA technology – based industrial production of proteins and peptides to manage root-knot nematode. Mi gene resistance in tomato plants has been utilized to manage M. incognita and M. javanica. Also, protoplast fusion between Pseudomonas fluorescens and P. aeruginosa to manage M. inc...
Ji Xu, Zhonghua Liu, Zhenhai Cui and Wenhai Zhao*
...gate the effect of gross saponins of Tribulus terrestris (GSTT) on chondrocyte injury induced by IL-1β and its possible mechanism. Chondrocytes were isolated from rat knee joints and cultured. Chondrocytes were treated with IL-1β, and chondrocytes were treated with different concentrations of GSTT. ELISA was used to detect the levels of IL-6, TNF-α and IFN-γ. Flow cytometry was used to detect the apoptotic rate. The expressions of Bax, cl...
Mimi Syazwani Jaapar1, Eric Lim Teik Chung1,2*, Nazri Nayan1, Mamat Hamidi Kamalludin1,2, Mookiah Saminathan3, Kalai Vaani Muniandy2, Muhammad Hazziq Mohd Hamdan1, Shokri Jusoh1, Faez Firdaus Abdullah Jesse2,4
...he presence of steroidal saponins. Therefore, the main objective of this study was to determine the effects of different levels of B. decumbens diets on the in vitro gas production and ruminal fermentation characteristics. Graded levels of B. decumbens were mixed with P. purpureum, where 10% was identified as the low-level B. decumbens diet (T2) and, 60% was identified as the high-level B. decumbens diet (T3) based on the concentration of
A.A. Tanimola† and B. Fawole1
...ls:
tannins, saponins, flavonoids, cardenolides, phenols, alkaloids and anthraquinones. However, total phenol (14.3
mg/g), tannins (14.5 mg/g) and saponins (59.8 mg/g) were highest in AKY than in other aloes. Flavonoid content
(3.7 mg/g) was highest in AAR while alkaloid content was highest in AST. The infrared analyses revealed that the
Aloe species had similar functional grou...
SYED ZULFIQAR ALI ABIDI, HAFIZ ABDULLAH SHAKIR, SYED SHAHID ALI, & JAVED IQBAL QAZI*
...nnine, free amino acids, saponins, tannins, terpenoids, quinine, oxalic acid and steroids). Twenty one plants showed the presence of phytochemicals. The use of piscicidal property of these plants may improve the production of aquaculture by getting rid of unwanted fish species.
Key Words: Alcoholic extract, Aqueous extract, Phytochemicals, Metabolites, Plants
... 
Riswandi1*, Ali Aim1, Muhakka1, Afnur Imsya1, Agus Wijaya2
...tochemicals (tannins and saponins), including water mimosa, giant molests, and water chestnuts. The objective of this study was to evaluate the effect of swamp forages combination in the ration on the characteristics of rumen fermentability and methane production. The design used was completely randomized design (CRD) with 4 treatments and 4 replications. The treatments given were A (guinea grass and concentrate, 7:3), B (guinea grass, water mimosa and concent...
Abdur Rauf1*, Farooq Jan1, Muhammad Qayash2, Zia-ul-Islam3, Rizwanullah1, Ikramullah Khan1, Muhammad Shuaib4, Muhammad Khalid5 and Samrin Gul6
...e presence of alkaloids, saponins, flavonoids, and phenols in the ethanolic crude extract....
ZAMARA MASOOD1, FAROOQ SALEEM1, SARFRAZ AHMAD2, TALHA JAMSHAID3, IMRAN WAHEED4,
MUHAMMAD AZEEM1, UMAR FAROOQ GOHAR5 & HAFIZ MUHAMMAD ARSALAN6, 7*
...des, cardiac glycosides, saponins, flavonoids, cumarins, steroids,
proteins, and amino acids, fixed fats and oils in all fractions. Floral
extracts were found to contain highest total phenolic contents (64 to 73
mg GAE/g), whereas leaves n-hexane fraction exhibited maximum DPPH
potential (70 %). All the extracts showed promising antimicrobial activity
in terms of zone of inhibition against selected ba...
SHEHLA AKBAR*, SAIQA ISHTIAQ*, KHALID HUSSAIN, ANS MUNIR & SAIRA REHMAN
...67 μg/ml), total glycosaponins (14.95%),
total alkaloids (24.67%), total polyphenolics (28.40%) and total flavonoids
(5.67%) were found in given plant samples. were found in the samples.
Haemolytic and DNA protection studies of Misopates orontium were also
performed. Solar protection factor was calculated of all fractions by
adopting the standard procedure. By using concentration 200μg/ml and
Orooba Mohammed Saeed Ibrahim1*, Rawaa Saladdin Jumaa2, Nibras Zeyad Yahya1
...ce of alkaloids, phenol, saponins, flavonoids, tannins, and glycosides. The test organism was more sensitive to C. limonum compared to C. aurantium. The MICs ranged from 1.56 to 12.5mg/ml; MBCs, (3.125 - 25mg/ml) and MBC/MIC ratios (2.0-4.0). Furthermore, a time killing curve of each 4x MICs and 8x MICs concentrations of juice extract showed a distinguished bactericidal effect at 6th hr. Therefore, the use of citrus fruit juice as medicine to treat infections ...
Sara H. Zughayyar*, Amer H. Gyad
...ols, resins, flavonoids, saponins, alkaloids, coumarins, terpenes, and glycosides, while steroids and proteins were absent. The extract displayed antidiarrheal activity comparable to loperamide, showing a significant reduction in intestinal content volume and weight (P≤0.05). In conclusion, the ethanolic extract of Prosopis farcta L. fruits demonstrated promising antidiarrheal activity, potentially due to the phytochemical constituents identified, warrantin...
Oghenebrorhie M. Oghenochuko1,4*, Olubukola T. Adenubi3, Olusola L. Ajayi3, Fakilahyel M. Mshelbwala3, Johnny O. Olukunle3, Samson A. Rahman3 and Godfrey N.O. Ezeri2
.../l), flavonoids (0.46%), saponins (0.28%), tannins (0.95%). PCV, Hb, RBC and WBC were increased in all treatments but values were higher in bath treatment for RBC (3.0×1012/L), PCV (32.7%), Hb (10.7%). MCV, MCH and MCHC showed similar trend. Similar trends as in RBC and WBC were observed in total proteins. Liver and kidney functionality as expressed by ALT, AST, ALP, creatinine and BUN exhibited no damaging effect on organs. Degenerations were observed i...
Rizk, Sonia A.; El-garf, Eman M. and Talaat, Abeer A.
Tabinda Nowsheen1, Sayed Wadood Ali Shah2, Ali Hazrat1*, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar4 and Muhammad Ajmal Khan3
... flavonoids, terpenoids, saponins, tannins, phenolics steroids and carbohydrates but deficient of proteins. In minimum inhibitory concentration assay, the crude methanolic extracts showed significant inhibition against all tested bacterial strains at25, 50 and 100 µg/ml. The methanolic crude extract of A. maritime various parts showed MIC of 37.5µg/ml for S. aureus which is gram-positive bacteria followed by 75µg/ml for P. aeruginosa, (gram n...
ASIFA BASHIR1, AAMIR MUSHTAQ2* & TOOBA MEHBOOB3
..., alkaloids, flavonoids, saponins, glycosides, amino acids and proteins in crude extract with phenolic and flavonoid contents observed as 9.9 mg/g equivalent of gallic acid and 100 mg/g equivalent of rutin, respectively. Free radical scavenging activity by plant extract was observed as 68±0.33 % as compared to rutin (58±1.15 %) at concentration 2.56 mg/ml. Similarly, in vivo studies indicated that Phyllanthus emblica 80 mg/kg significantly reduce...
Shah Zeb Khan1, Ali Hazrat1*, Farman Ali Khan2, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar3, Muhammad Ajmal Khan4 and Hayat Ullah1
...kaloids, glycosides, and saponins) in the bark of V. negundo (L.) roots and stem, as well as their potential antioxidant and antibacterial properties. The crude was obtained in 95 % methanolic which was further fractionated into n-hexane (HR, HS), Chloroform (CR, CS), ethyl acetate (EtR, EtS) and butanol (BR, BS) soluble fractions by solvent-solvent extraction. In phytochemical tests of roots fractions; HR showed the presence of terpenoids, while
Zara Naeem1, Khajista Jabeen1*, Muhammad Khalid Saeed2, Sumera Iqbal1
...vealed the occurrence of saponins, alkaloids, coumarins, flavonoids, and tannins while the plant was devoid of terpenoids, phlobatannins, and glycosides. Hence it can be concluded that the methanolic leaf extract of the tested plant effectively inhibited the growth of test mycotoxigenic fungi....
Suherman Suherman1*, Muhammad Fahri Rizky1, Zaki Bahrul Fikri1, Hadiyanto Hadiyanto1, Zane Vincevica-Gaile2, Anwar Saeed Khan3, Erkata Yandri4,5 and Iswahyudi Iswahyudi6
...ls, flavonoids, tannins, saponins, and essential oils. Agricultural products are still dried using conventional methods. Although, traditional drying is relatively simple, it has disadvantages such as relatively long drying time, relatively low drying quality, significant damage, and the sun’s ultraviolet rays can also damage the chemical components of dried materials. Therefore, a new drying process technology, Photovoltaic Ventilation (Solar Dryer) was...
Estrelle Anne Tacbas1, Neil Pep Dave Sumaya2 and Nanette Hope Sumaya1,3*
...f alkaloids, flavonoids, saponins, steroids, and tannins in both plant crude extracts. Different developmental stages of C. elegans (i.e., 1st to 4th larval stages (L1-L4), young adult (YA) and adult nematodes) were used for in vitro anthelmintic assay, mortality, development of life stages, and reproduction of the nematode. Both plant extracts caused high mortality in the L4 stage for their LC50 and LC90 values. Notably, the crude extracts of both plants dela...
Yusuf Subagyo*, Merryafinola Ifani, Hermawan Setyo Widodo
...iterpenoids, flavonoids, saponins, carbohydrates, and tannins. Few toxic compounds, such as tannins in C. calothyrsus, were not at harmful levels. The ethyl acetate fraction has higher toxicity 13.34±5.78; 50.00±10.00; 100.00±0.00% and hexane as lowest 6.67±5.78; 20.00±0.00; 60.00±10.00%. Fraction from 50% Ethanol extraction has the lowest LC50 (560.63ppm). Replacement of concentrate using dried C. calothyrsus in the d...
Nur Anis Hashim1, Nor Hasima Mahmod1*, Abubakar Abdullahi Lema2, Lee-Hoon Ho3 and Mohammad Moneruzzaman Khandaker1
...s anthocyanins, tannins, saponins, glycosides, flavonoids and terpenoids. The findings demonstrated that fresh calyx retained the highest antioxidant capacity, thus providing insights into post-harvest processing of the calyx.
...
Syarifah Nurul Waqiah1, Ratmawati Malaka2*, Ambo Ako2, Sadam Suliman Mohamed Yousof3, Hanif Uzwa Hasanah Sudirman4
...e (days), the content of saponins (exist/not exist), tannins (%), flavonoids (ppm), and pH on herbal sprays. The results revealed that the measurement of wound area in dairy cattle after herbal sprays at P0=0.66 cm, P1=2.22 cm, P2=0.06 cm, and P3=0.00 cm; wound drying time was faster at P0=11 days, P1=9 days, P2=8 days, and P3=5 days; and significantly faster wound healing time at P0=14 days, P1=12 days, P2=11 days, and P3=10 days. The compounds of the herbal ...
Herna Febrianty Sianipar1,2,3, Wahyu Widoretno1, Luchman Hakim1, Rezi Rahmi Amolia4, Fatchiyah Fatchiyah1,2,5*
...r alkaloids, flavonoids, saponins, tannins, phenolics, and quinolines. Aglaia tomentosa contains the highest total flavonoid content (23.27 ± 3.46 mg QE/g). The bioactive compounds found in Castanopsis argantea consist of caffeine and flazin. Artocarpus heterophyllus comprises Synephrine and Schinifoline while Aglaia tomentosa consists of Artoindonesianin B and 2,5-Di-tert-butylhydroquinone. The highest antioxidant was found in Artocarpus heterophyllus ...
Afshan Kaleem*, Iqra Noor, Roheena Abdullah and Mehwish Iqtedar
...s, proteins, glycosides, saponins, phenols etc. Antibacterial analysis of aqueous extracts of Phaseolus vulgaris and Vigna unguiculata were done by using the disc diffusion method, which showed that both extracts have potential antibacterial activity against Staphylococcus aureus and Escherichia coli, though Phaseolus vulgaris has higher antibacterial activity than Vigna unguiculata. FTIR and in silico analysis showed that the aqueous extracts of both Vigna un...
Madeeha1, Shahida Naveed1*, Ayosha Hanif1, Jalwa Afroz1, Abdul Haq1, Gul Rose2, Inayat Ullah3 and Zunaira Inayat4
..., proteins, steroids and saponins. Various extracts of Olea ferruginea leaf nut galls were screened for antimicrobial activity at 100mg/ml concentration level against four bacterial species including two gram positive bacteria (Staphylococcus aureus and Streptococcus mutans), two gram negative bacteria (Escherichia coli and Salmonella typha) and one yeast species (Candida albicans) using agar well diffusion method. Among the extracts, methanol was found best s...
Andriantsihoarana J. Razanatseheno1; Lovarintsoa J. Randriamampianina1; Hanitra R. Randrianarivo1; Danielle A. D. Rakoto1; Victor L. Jeannoda1*
Novel Research in Microbiology Journal (2019), 3(6): 502-510
... contained alkaloids and saponins. The antimicrobial activity was tested against many bacteria spp. including; Listeria monocytogenes, Staphylococcus aureus, Clostridium perfringens, Enterobacter aerogenes, Salmonella enterica, Shigella flexneri, and Vibrio fischeri, using the Disc diffusion and the Microdilution assays. With the exception of the SME which is inactive, the other extracts exhibited broad spectrum potential against all the tested bacteria. The a...
Abdulaziz Yahya Al-Ghamdi
Novel Research in Microbiology Journal (2022), 6(2): 1515-1529
...t the extracts contained saponins; coumarins, alkaloids, tannins, flavonoids and steroids. Gas chromatography-mass spectrometry (GC/MS) analysis revealed the presence of 38 different compounds in the ethanol extract, 41 compounds in chloroform extract, and 27 compounds in the aqueous extract. As the concentration of the ethanol extract increased from 25 mg/ ml to 300 mg/ ml, the in vitro antimicrobial potency against the tested microorganisms increased. At 50 ...
Manan Kumar1, Sony Eka Nugraha2*, Nabila Nabila3
...s; and the foam test for saponins. The Microwave-Assisted Extraction (MAE) method was used to extract compounds from the beetroot tubers. Furthermore, diabetic rats were induced via a single intraperitoneal injection of streptozotocin at a dose of 65 mg/kg body weight (BW), which was administered 15 min after the administration of nicotinamide at 110 mg/kg body weight. Diabetic rats were subsequently administered varying doses of Beta vulgaris L. ethanol extra...
Zia Ur Rahman1*, Naveed Ahmad1, Adnan Ahmad2, Muhammad Idrees1, Faisal Bashir2 and Sher Ali Khan2
...h as tannins, alkaloids, saponins and protein playing a vital role in enhancing vigor and fertility of both men and women. Asparagus officinalis exhibits pharmacological characters and work as an active anti- inflammatory, anti-oxidant, anti-abortifacient, anti-cancer, anti-oxytocic, anti-cancer, anti- ulcer, anti -fungal, anti-coagulant and anti-bacterial. It has been reported to use as a prominent remedy for reducing risk of cardiovascular diseases, osteopor...
Suanyuan Zhang, Qing Ji, Xinglong Wu, Jinjing Wang, Jin Yao, Chengfang Li, Xiaorong Yang, Na Tan, Jing Yang and Hong Zheng*
...naxadiol type triterpene saponins in ginseng, which has anti-inflammatory/cancer/diabetic impacts. To investigate the molecular mechanism in which GRh2 reduced inflammation of UC via upregulating microRNA (miR)-30a-5p, we detected miR-30a-5p in the tissues and serum of patients with active UC and in NCM460 cells after dextran sulfate sodium (DSS) treatment. Inflammation factors, nuclear factor-κB (NF-κB) and p65, were detected in NCM460 cells intro...
Pakistan Journal of Zoology
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