Gultaj Hussain1, Abdur Rahman1*, Tariq Hussain2, Siraj Uddin1, Tariq Ali3
E-mail | [email protected]
...act | Preservative and antibacterial effects of citric acid and lactic acid treated beef were studied previously on Escherichia coli O157: H7 and Salmonella typhymurium. This was aimed to investigate the effects of these acids on the total viable count (TVC) of these bacteria. Three diluted concentra- tions (1.0, 3.0 and 5.0%) of both citric acid and lactic acid were used. A total of 3024 meat samples were collected from cattle slaughtered at Peshawar, Pakista...
Antibacterial Activity by Chlorogenic Acid Isolated through Resin from Apricot (Prunus Armeniaca L.)
Ahmed Mujtaba1, Tariq Masud1, Asif Ahmad1, Waqar Ahmed3, Saqib Jabbar3* and Robert E. Levin2
... studies concluded the antibacterial activity of apricot (Prunus armeniaca L.) and its by-products. The aim of the study were to test the activity of chlorogenic acid isolated from apricot cv. Habi, against different food borne pathogens and quantification of the chlorogenic acid (CA) using High Performance Liquid Chromatography (HPLC). The chlorogenic acid was isolated using resin. The recovered amount of compound was calculated. Aliquots of the extrac...
Bushra Niaz1,*, Tahir Zahoor1, Muhammad Atif Randhawa1 and Amer Jamil2
... for the evaluation of antibacterial activity of lactoferrin. Minimum inhibitory concentration (MIC) of lactoferrin was determined by 96-well plate method using ELISA reader. Results depicted that CM-Sephadex C-25 was a good cation exchanger for recovery of lactoferrin. Camel raw milk produced 2.4 mg/mL of lactoferrin. The lactoferrin isolated from camel milk exhibited promising antibacterial activity against E. coli ...
Obaidullah1, Zafar Ali Shah1* and Sami Ullah2
...cles followed by their antibacterial assessment. Lapachol was isolated from stem heartwood of heterophragma adenophyllum seem through column chromatographic technique. Characterization of Lapachol was carried through melting point assessment and running its comparative TLC against standard, added with structure elucidation by FT-IR spectrum. Silver nanoparticles of Lapachol were synthesized by treating 1 mM silver nitrate (AgNO3) solution with 1 mM solut...
Saba Irshad1,*, Ayesha Ashfaq1, Ammara Muazzam1 and Abida Yasmeen2
...xtracts showed maximum antibacterial activity against B. subtilis, E. coli and S. aureus. All alcoholic extracts were competent enough to reduce the growth rate of M. canis and A. flavus up to 35%, with no inhibitory influence on Candida species and F. solani. These extracts fully inhibit growth of PC3 cells. Moreover, partially purified lectin, from Curcuma longa L. with a molecular weight of 17.3 KDa mi...
Jawad Anwar* and Zafar Iqbal
...or novel and effective antibacterial compounds to treat, prevent and resist is highly demanded. Luckily fungi are potential producer of antibacterial natural products. The present study was initiated to investigate the antibacterial activity of Trichoderma harzianum against phyto and human pathogenic bacterial strains. T. harzianum was grown under different conditions and their extracts we...
Muhammad Usman Qamar1, 2, Sidrah Saleem1, Usman Arshad1, Muhammad Farhan Rasheed3, Hasan Ejaz4, Naveed Shahzad5 and Shah Jahan6,*
... by VITEK 2 system and antibacterial activity, MIC and MBC of manuka honey was performed by agar well diffusion assay and microbroth dilution assay respectively. All isolates (n=5) were carbapenamase and MBL producers andNDM-1 gene carrier. These isolates displayed significant resistance against commonly used antibiotics including carbapenem and colistin proved to be most effective drug. Manuka honey manifested significant antiba
Jing Xin Mao1,2, Guo Wei Wang2, Yuan She Huang3, Rui Wang2, Guo Ze Wang4, Bing Zeng1 and Fu Yuan Zuo1,*
...fference expression of antibacterial related gene among indigenous breed (Rongchang pig) and artificially cultivated breed (Landrace), The Rongchang pig (0 day old, 28 day old, 120 day old) and Landrace BPI (0 day old, 28 day old, 120 day old) gene were expressed in normal liver, heart, lung, kidney, spleen and small intestine. The results showed that: The expression level of BPI in lung of Rongchang pig was relatively higher level compared to that in heart, l...
Alim-un-Nisa1*, Sajila Hina1, Sania Mazhar1, Imran Kalim1, Ijaz Ahmad1, Naseem Zahra1, Shahid Masood1, Muhammad Khalid Saeed1, Qurat-ul-Ain Syed1 and Maida Asif2
...l growth rather it has antibacterial activity. The lethal dose and toxicity determination of the color extracted from marigold showed that it is safe for consumption as no clinical symptoms were observed in rabbits after giving the maximum dose of 1000ml of color.
...
Nina Bao1,*, Yongguang Yin2 and Panpan Wang3
...hat the extraction has antibacterial activity, and the purified one is better than the crude one.
...
Mehwish Aftab, Tariq Mahmud*, Muhammad Asim Raza Basra, Aqsa Gulzar, Sumaira Basharat and H.M. Junaid
...(III) complexes showed antibacterial activity against E. coli, S. aureus by disc diffusion method and antifungal activity against Macrophomina phaseolina, Fusarium oxysporum. The metal (III) complexes are highly active under permissible limits.
...
Nadia Khan1*, Abdul Waheed1, Farrukh Siyar Hamid1, Naveed Ahmed1, Zafar Iqbal2, Seemab Ali1, Madiha Bashir1 and Hina Gul3
...chemicals and in vitro antibacterial activity against two phytopathogenic bacterial species (Clavibacter sp. and Xanthomonas sp.) and a human pathogenic bacterium (Escherichia coli) in 2016. Experiment was carried out by using complete randomized design with three replications in vitro. Phytochemical analysis reveals that the methanolic fraction of oil possesses metabolites like carbohydrates, amino acids, alkaloids, flavonoids and glycosides. To test the an
Hao Gu*, Zhi Yang, Weiqiang Yu, Kan Xu and Yuan-fei Fu*
...elected to explore the antibacterial activity against the four cariogenic bacteria in terms of acid producing and biofilm. The antibacterial activity of capsaicin was evaluated by the minimal bactericidal concentration, change of pH in the first 12 h and OD values of biofilms. Besides, fluorescent images of exopolysaccharides and living bacteria of Streptococcus mutans were measured with confocal laser scanning micros...
Sabi-Ur-Rehman1, Anwar Khalid2, Qazi Najam Us Saqib3, Farooq Ahmad1, Shaheed-Ur-Rehman4, Neelam Zaman3, Ayeza Mehmood5 and Abdul Samad6*
... out, include in-vitro antibacterial and antifungal screening of aqueous methanolic extracts as well as crude saponins isolated from leaves and roots of Sarcococca saligna, using disc diffusion method. The tested bacterial strains include, B. subtilis, E. coli, S. aureus, P. fluorescens and fungal strains were Aspergillus. niger, A. flavus, and D. turcica. The maximum zones of inhibition, 23.00±0.56 mm and 25.00±0.50 mm was given by ethyl acetate...
Tahira Moeen Khan* and Amat ul Mateen
... show very significant antibacterial activity against four bacterial strains three gram negative (Escherichia coli, Proteus mirabilis, Salmonella) and one gram positive (Clostridium tetani). The minimum concentration of leaf extracts needed against these bacterial strains were also calculated. The present study indicated that Melia azedarach and Morus nigra leaf extracts can be used successfully for nanoparticles synthesis and CuO a...
Jie Yang
...lycan, and function in antibacterial immunity and inflammation. Mammals have four PGRPs (PGLYRP1, PGLYRP2, PGLYRP3 and GLYRP4). They are secreted proteins expressed in different tissues. It is significant to make a study of human PGLYRP1 because neutrophils are a more dominant mechanism in human host defense. Related research results show the functions of human PGLYRP1 in the innate immunity of neutrophils is to conducive to the killing of intracellular and ex...
Fan Yi1,2, Xiaobin Yang1, Shigen Ye1, Hua Li1 and Ruijun Li1,*
... for its antiviral and antibacterial activities. In this study we are investigating the effect of HCT in aquaculture animals. In this study, 300 olive flounders (Paralichthys olivaceus) were stochastically divided into four experimental groups: basal diet feeding group, 0.5% HCT continuous feeding group, 1% HCT feeding group, and 1% HCT interval feeding group. Three replicates were set for each treatment, and 25 fish were stocked on each replicate. The ...
Lin Qi, Lu Li, Danyang Chen, Mingxiao Liu, Yan Wu and Wei Hu*
...peptide sequencer. The antibacterial activity of the protein monomer in antlerplate was studied by disc diffusion method, and the antibacterial ring diameter of each antibacterial agent was measured to determine its antibacterial ability. The molecular mass and purity of this polypeptide was 18.970kDa and 90%. Amino acid sequence analyses indicated that ...
Mohammed Al Bratty1,*, Hassan A. Alhazmi1,2, Desam Nagarjuna Reddy3, Abdul Jabbar Al-Rajab3, Sadique A. Javed1 and Zia ur Rehman1,4
...microorganisms for its antibacterial and antifungal activities. The major classes of compounds indentified in the extract were fatty acid esters and aliphatic hydrocarbons. Methyl-(7Z)-7-hexadecenoate, methyl-(9E)-octadecenoate and methyl tetracosanoate were found to be the principal fatty acid esters, while E-pentatriacont-17-ene and 2,4-dimethylpentane were identified as predominant aliphatic hydrocarbon compounds. The propolis extract has exhibited remarkab...
Nazish Mazhar Ali1, Asma Ashraf 2*, Iram Liaqat2, Bushra Mazhar2, Shaukat Ali2 and Saiqa Andleeb3
...g on selective medium. Antibacterial activity of different compounds was observed against the pathogenic bacterial isolates. Minimum Inhibitory Concentration (MIC) test of different kinds of honey was performed against the isolated bacterial pathogens. The antibacterial activity of leaf extract of Azadirachta indica (Neem Plant) was also checked against the pathogenic bacterial isolates. The bacterial pathogens isolat...
Muhammad Naeem Khan* and Asad Jan
...displayed considerable antibacterial activity against Xanthomonas campestris and Pseudomonas aeruginosa causing 12.6±0.54 mm and 20.6±0.53 mm zone of inhibition, respectively which was analogous to that of cefixime, used as standard drug. In case of antifungal activity MCE hindered the growth of Fusarium oxysporum effectively, causing 19.3±0.41 mm zone of inhibition, while the activity of other solvent was moderate. ...
Hafiz Muhammad Tahir*, Palwasha Jabeen, Chand Raza, Shaukat Ali
... been found to possess antibacterial properties and application in culturing tissues including skin, bone, cartilage and nerves. Sericin has been hailed to have antitumor activity and has also been widely used in different cosmetics. The major hindrance in using spider silk for different purposes is due to its small obtainable amount. Efforts are being made to overcome this problem by modern biotechnological techniques including of making transgenic organisms....
Barkat Ali1,2, Wasim Sajjad1,2,3, Imran Khan1, Muhammad Rafiq1, Sahib Zada1, Aamer Ali Shah1 and Fariha Hasan1,*
...RNA sequence analysis. Antibacterial activity of the isolates was checked against ATCC strains E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Seven different types of antibiotic discs were used to check the intrinsic resistance of all the isolates to various antibiotics. Interestingly, most of the isolates were found resistant while only a few were susceptible, however, the isolates Lysinibacillus spp. N40...
Mohammad Ejaz1, Salma Javed2, Muhammad Hamza1, Sadia Tabassum2, Muhammad Abubakar3, Irfan Ullah4*
...used as antimicrobial, antibacterial and anticancer agents. Fungal endophytes like Taxomyces andreanae isolated from Yew plant have the potential to produce an anti-cancer compound called Paclitaxel. Other different fungal endophytic species produce various other types of anticancer compounds like camptothecin, podophyllotoxin, torreyanic acid, vincristine, and vinblastine. This review is organized to describe the general study of natural bioactive mole...
Anurag Sharma*, Naresh Kumar, Geetanjali Singh and Anika Sharma
...ic, anti-inflammatory, antibacterial, antifungal and galactagogue activity. The commercially available drugs pose health threats and prove detrimental to both human and animal health. The traditional use of herbal preparations suggests that they are safe and effective, however, scientific validation is still required for many of them especially for animal use. The phyto-pharmacological research on these two natural products show a ray of hope for the discovery...
Sumaira, Ali Mujtaba Shah*, Ghulam Asghar Solangi, Ifra Anwar, Qudratullah Kalwar
...ts, such as antiviral, antibacterial, anti-diabetic, anti-carcinogenic and anti-ageing. Besides, camel milk contains abundant proteins which are conductive to improve the immunity functions. Thus, it is necessary to illuminate the beneficial impact of camel milk and its composition.
Safia Arbab1, Rehana Buriro1, Shams Uddin Bhugio1, Atta Hussain Shah2, Jamila Soomro3,Qudratullah Kalwar4, Saqib Ali Fazilani1 and Waseem Ali Vistro5*
...ite the exploration of antibacterial activity of the Aloe Vera in different families of animals. However, very limited information is documented about antibacterial activity of Aloe Vera in equines. The present study was designed to check the antibacterial activity of the Aloe Vera against most pathogens found in the wounds of donkey. For this purpose, two different concentrations 30 &micr...
Tahseen Ullah* and Noor ul Amin
In Vitro Antibacterial Activity of Medicinal Plant Extracts
..."text-align: justify;">Antibacterial activities of four medicinal plants, Silybum marianum, Berberus lycium, Peganum harmala and Curcuma longa and standard antibiotic tetracycline was carried out in the biosafety level 3 Microbiology Lab, Faculty of Life Sciences, University of Bradford, Bradford, UK. Two different concentrations (low, 5 mg/ml and high extracts, 300 mg/ml) of these plants were evaluate against two different bacterial strains i.e. Bacillus subt...
Ayesha Talib1,2, Khanzadi Nazneen Manzoor1, Wajahat Ali1, Maria Saeed1, Muhammad Asif Gondal1, Malik Badshah3 and Abid Ali Khan1*
...icles showed promising antibacterial activity against MDR clinical isolates of bacteria.
...
Asma Chaudhary1, Qurat-ul-Ain Ahmad1, Afia Muhammad Akram1, Sadia Roshan2 and Javed Iqbal Qazi3*
...well as in vivo antibacterial and probiotic potential of Sphingomonas sp. AsCh-P3 (MF543123) and Bacillus aerius AsCh-A7 (MF543123) against fish pathogen Pseudomonas fluorescens. Antagonism by cross streak was observed in ten isolates out of total twenty. Six isolates showed better inhibition by well as well as disk diffusion methods with maximum growth inhibition zones i.e., 15 and 17 mm by Sphingomonas sp. AsCh-P3 an...
Asma Chaudhary1, Qurat-ul-Ain Ahmad1, Afia Muhammad Akram1, Mehwish Iqtedar2 and Javed Iqbal Qazi3,*
...otic treated feed with antibacterial potential against V. anguillarum was administered to experimental fishes in different groups; G1 (soon after challenge for 30 days), G2 (for 15 days prior and 30 days after challenge) and G3 (for 15 days prior to challenge). The survival rate of fishes was 60% in C2, 66% in G1, 83% in G2 and 76% in G3. Fishes subjected to V. anguillarum (C2) showed significant decrease in growth and biochemical constituents as...
Phytochemical and Antimicrobial Potential of the Roots of Berberis brevissima Jafri. (Berberidaceae)
Zain Ullah1*, Anwar Ali Shad1 and Saqib Ali2
...R data techniques. The antibacterial assays of the obtained six oil sub-fractions (H-1 to H-6) were accomplished against S. epidermis, E. coli, and S. aureus bacterial strains and the results ranged from 10-18 mm zone of inhibition. The GC-MS analysis of the six oil sub-fractions (H-1 to H-6) confirmed the existence of linoleic acid, palmitic acid, and oleic acid in the highest amount....
Fahrauk Faramayuda1,2*, Totik Sri Mariani3, Elfahmi1,4 and Sukrasno1
...nd Southern Asia as an antibacterial, antidiabetic, antihypertensive anti-inflammatory. The country of Indonesia has three varieties of O. aristatus, namely purple, white-purple and white. The purple and white-purple population has started to decline. Efforts are needed to maintain the two varieties’ population, one of which is plant tissue culture. It is hoped that in vitro cultured plants contain the same secondary metabolites as the wild type. This st...
Chao-Qun Shi1, Hong-Ying Lin1, Jin-Qing Zheng1, Fan Yang1, Kwame Ayisi Lartey1, Dan-Ju Kang1, Hwa-Chian Robert Wang2, Ravi Gooneratne3*and Jin-Jun Chen1*
...orata (TFCO) as an antibacterial agent in vitro, and the mechanism of action of TFCO in combating Escherichia coli-induced diarrhoea in mice. MBC and MIC values of 0.25 and 0.125 g TFCO/ml showed it was effective as an antibacterial agent against E. coli (CMCC 44752) in vitro. Ninety Kunming mice were randomly divided into five groups of 18 mice per group (1 male: 1 female). The groups were co...
Rosidah Rosidah1*, Angga Nugraha1, Yuli Andriani1, Kiki Haetami1, Olga Anne2 and Agus Heri Purnomo3
... has the ability as an antibacterial with inhibition zone diameter reaching 20.49 mm at a concentration of 5 000 mg kg–1 and LC50 test 48 h (in vivo test) of 1 157.16 mg kg–1, so for the treatment of fish use concentrations below that concentration. The use of aloe vera extract with a concentration of 300 mg kg–1 for 48 h was effective to treat koi fry infected with A. hydrophila
Hafiz Muhammad Tahir*, Iram Liaqat*, Junaid Nadeem, Hammad Aamir and Shaukat Ali
... spider silk possesses antibacterial potential dates back to the time of ancient Greece when it was frequently used as wound dressings. In recent years, several studies have investigated the alleged antibacterial potential of spider silk but the results have largely been inconclusive. The studies either failed to consider the inhibitory effects of the processing chemicals or did not investigate whether the inhibitory potenti...
Xiaoli Cai1,2, Saeed Ahmed3, Zhixin Lei1,*, Jianping Wu1,* and Taolei Sun1,2,*
...rge. Additionally, its antibacterial drug encapsulation can make it easier to enter the cell and improve the concentration in the target tissue. In the current review, the purpose is to find a more effective nanometer system to fight against intracellular bacterial infection. Current observation describes the drug resistance mechanism of bacteria, the bactericidal mechanism of antibiotics, the way of nanoparticles overpasses the cell membrane and approaching t...
Amir Z. Allam, Hayam A. Mansour, Nermeen M.L. Malak, Heba H.S. Abdel-Naeem*
... due to their powerful antibacterial action and increasing consumer concerns about synthetic preservatives. However, applications of EOs in food have been hampered by their pungent odor, which has a negative impact on customer acceptance. Therefore, this study was conducted to investigate the effect of using low concentration (0.002%) of thyme (T), oregano (O), clove (CL), and their combination (TO, TCL, OCL, and TOCL) on the bacterial quality of chicken meat ...
Alshimaa A. Hassanien1*, Asmaa Osama Tolba2, Asmaa A. A. Hussein3, Walaa M. Elsherif4
...-lactalbumin exhibited antibacterial effect on S. aureus isolates. Therefore, they can be used in food industry and human therapeutics but needs further studies for the best application methods.
Keywords | S. aureus, Meat products, Food handlers, 23S rRNA sequencing, Casein, α-lactalbumin
...
Rasha Ali Taha Hamza1, Atef Saad Osheba1, Hassan Mohamed Sobhy2, Sahar Hussein Abdalla Hekal2*
...ve than gram negative. Antibacterial activity of different galangal and sumac extracts against total bacterial count was more effective in burger prepared with Sudanese meat than burger prepared with Brazilian meat, where the highest synergistic antibacterial activity were recorded with the combination of Galangal and sumac extracts (250ppm Galangal +250ppm Sumac), which ranged from 1.75×104 and 5. 75×104 at zero...
Jiang Wu*
...s aimed to investigate antibacterial activity of chemical constituents of Taraxacum officinale against foodborne pathogens. A total of 133 retail meat products were randomly purchased from different supermarkets. All samples were isolated and identified by conventional methods as Staphylococcus aureus, Salmonella, Escherichia coli and Listeria monocytogenes. Different bacteria were respectively inoculated into LB medium, the OD600 was adjusted to 0.5, and the ...
Sri Melia1*, Indri Juliyarsi1, Yulianti Fitri Kurnia1, Evy Rossi2, Hurriya Alzahra3
...ria were found to have antibacterial activity against pathogenic bacteria such as E. coli, Pseudomonas, Listeria inokua and Klebsiella pneumonia. Base on the phylogenetic analysis, the bacteria isolated were closely related to Limosilactobacillus fermentum, a probiotic bacteria candidate.
Keywords | Lactic acid bacteria, Limosilactobacillus fermentum, Antimicrobial, Probiotic
...
Aiman Al-Mufarji1, Abd El-Nasser Ahmed Mohammed1*, Haitham Al-Masruri2, Rashid Al-Zeidi3
...r purified compound as antibacterial, antiviral, antioxidant and anti-tumour have been well established. The valuable chemical constituents of microalgae include “proteins, polysaccharides, lipids, PUFAs, vitamins, pigments and other bioactive compounds”. The microalgae composition varies depending on species and nutrient availability for production. Genetic engineering might be used for production invaluable microalgae compounds. Microalgae consid...
Muhammad Ajmal Khan1, Muhammad Yahya2*, Ali Hazrat2, Javed Khan3, Saeed Jan4, Tabinda Nowsheen2 and Inam Ullah5
...nts, antioxidants, and antibacterial activities of methanolic extracts of T. camphoratum leaves. The methanolic extract was quantitatively evaluated for alkaloids, flavonoids and terpenoids contents. The antibacterial activity of methanolic leaves extract of T. camphoratum was carried out against Gram-positive and Gram-negative bacterial strains through agar well diffusion assay (small wells were made with cork borer and 6&m...
Heba S.S. Salem1, Hend M. Megahed2, Marwa M. Sarhan2, Maha M. El Alem3, Gehan N. Alagmy3*
...ts.
Keywords | Antibacterial Activity; Bee Venom; Staphylococcus aureus; Septic Arthritis
...
Hurriya Alzahra1, Susmiati Susmiati2*, Sri Melia3
...pecifically the Lactiplantibacillus pentosus HBUAS53657. This study aims to determine the antioxidant activity, total phenol, and organoleptic characteristics including the taste, aroma, and texture of fermented milk with orange juice added (Citrus nobilis L.). The study was based on a Factorial Completely Randomized Design (CRD), with starter concentrations of 4 (A1), 5 (A2), and 6% (A3), as well as orange juice concentrations of 10 (B1), 15 (B2), and 20% (B3...
Fawziah M. Albarakaty*
...ile also examining the antibacterial, antifungal efficacy of plum (Prunus domestica L.) peel extracts on certain crucial аnimal microbes. Methodology: The antibacterial activity of plum (Prunus domestica L.) peel extracts in hоt and cold aqueous and ethanol extracts against specific medically significant pathogens isolated from cows and poultry farms were assessed. Additionally, the phytochemical composition of the aqueous...
Farzana Bashir2, Aysha Saleem1, Khalid Iqbal Khichi2, Rubina Nelofer3* and Rauf Ahmad Khan2
...CP-OES techniques. The antibacterial activity was determined by column studies using response surface methodology (RSM) based on three levels, three factorial Box Behnken Design (BBD). The significance of independent variables (flow rate, bacterial count and column height) and their interactions were tested by means the analysis of variance (ANOVA) with 95% confidence limits. The antibacterial susceptibility was optimized fo...
Ayesha Saeed1*, Farzana Kishwar2, Ahsan Nazir3, Sharjeel Abid4, Muhammad Abiodullah5, and Danial Ali6
...e study was to develop antibacterial dry sheet nanofiber mask loaded with leaf extracts of MA and HRS as antibacterial agents in SA/PVA nanofibers through electrospinning method, which was just wet before its application. Leaf extracts were used at three concentration levels (0.5, 1, and 1.5 %). Scanning Electron Microscope (SEM) images confirmed the formation of optimized nanofibers with diameter range from ±49 to &p...
Mehwish Saleem1* and Amina Atiq2
..., and their all-around antibacterial effectiveness was assessed. To create garlic clove extract-based silver nanoparticles, 100 ml of distilled water was combined with 0.01g, 0.025g, and 0.05g extracts of both aqueous and ethanol to create 0.01%, 0.025%, and 0.05% extract solutions, respectively. All of these extracts were then mixed with silver nitrate to create a 0.01M solution of silver nitrate nanoparticles. UV-VIS was done for the characterization of the ...
Sayed H. Al Habty1, Dina N.Ali2*
...rin has a satisfactory antibacterial activity Minimum Inhibitory Concentration (MIC) at 10mg/ml and Minimum Lethal Concentration (MLC) at 40mg/ml. The results revealed that 40mg/ml LF in yogurt could inhibit MDR S. aureus at 2nd day while, 20mg/ml at the 4th day. The study concluded that LF can be used as a bio preservative in yogurt due to its highest antimicrobial activity and acceptable sensorial properties.
Keywords | MDR, Antibiotic resistance, Se...
Rinat Islamov*, Dinara Turegeldieva, Altyn Rysbekova, Kuralay Sarmantayeva, Victor Semenuyk
...aty has been shown. Rodentibacter pneumotropicus has been detected in the SPF animals, while no other pathogens from the FELASA list have been detected. The obtained results show the importance of not only regular health monitoring, but also the need to improve the quality of care and well-being of laboratory animals in some facilities of the Almaty city.
Keywords | Health monitoring, Mice, Rats, Rodent pathogens, Specific-pathogen free
...
Nuzhat Munawar1, Abrar Hussain1, Imran Sajid2, Zahra Noreen1, Muhammad Aslam3*, Zeeshan Rehman1 and Aamir Ali3,4
... active compounds. The antibacterial potential of various plant extracts was evaluated using well diffusion and disc diffusion assay against various disease-causing microorganisms. In the case of well diffusion assay, the plant exhibited a maximum 16mm inhibition zone against B. subtilis a minimum 10 mm inhibition zone against P. aeruginosa, with acetone extract. The same extract seems inactive against K. pneumoniae as compared to control. When tested on S. au...
Dina N. Ali1*, Sayed H. Elhabtey2*, Manal M. Amin1
...d spectroscopy (FTIR). Antibacterial activity of MO and Nano-MO was assessed against reference bacterial strains by using agar well diffusion method. The minimum inhibitory concentration (MIC) of MO and Nano-MO was 3% and 2%, on Listerea monocytogenes, Staphylococcus aureus, Salmonella typhi and E. coli bacteria, respectively. While, in inoculation of MO and Nano-MO in cheese complete reduction of examined bacteria was recorded at 3rd week of storage except fo...
Hesham A. Mahran1,2*, Shawky M Aboelhadid3, Saad S. Alqahtani4,5, Mohamed Z. Sayed Ahmed4,5
...dy was to create safe, antibacterial formulations based on cinnamon oil that were effective against Culex pipiens adults and pupae. Cinnamon nanoemulsion (CNE) was synthesized and characterized. The binary mixture of cinnamon with sesame oil (CS) was prepared at a rate of one part cinnamon to 3 parts sesame oil. Multiple concentrations from these formulations were prepared and tested against laboratory-reared adults and pupae of C. pipiens. The safety results ...
Van-Thanh Vo1, Thi-Hieu Tran1, Thi-Truc-Thao Nguyen1, Van-Tri Truong1, Cu-Thien Pham1, Thanh-Minh Pham2 and Huyen Nguyen Thi Thuong1*
....5% exhibited a higher antibacterial effect of essential oils....
Noor Rahmawati, Alfi Rumidatul* and Sopandi Sunarya
...ve compounds that have antibacterial and antioxidant activity. The method used in this study was to ferment endophytic fungi from gall rust sengon in different media, namely PDB, PDB plus sengon wood powder, and PDB plus yeast, for 9 days, followed by extraction using ethyl acetate solvent and testing of antioxidant and antibacterial activity. The DPPH radical was used to measure antioxidant activity, and Bacillus subtillis ...
TAHIR MEHMOOD*, ANUM AFZAL, ABDUL KARIM, MUHAMMAD ASHRAF SHAHEEN &
HINA ARSHAD
SADAF SARFRAZ1*, SAFDAR AMEER1, REENA AMBREEN1, SHOMAILA SIKANDAR 2, SHAISTA NAWAZ3 AND YASIR SALEEM3
... oil is found a potent antibacterial agent against all microbes used. Additionally, it was found that cinnamon samples collected from Sri Lanka has the highest oil content (3.1%), followed by China (2.8 %) and India (1.9 %), where all tests were standardised using fixed oil levels. In terms of antimicrobial properties, obtained results demonstrate that Indian cassia (Cinnamomum tamala) exhibited the highest an...
Sahar Ezeldien1,2, Foromo Dramou2, Fatma M. Yousseff3*, Alexander A. Nikishov2, Sergy B Seleznev2
...l plants known for its antibacterial, anti-inflammatory, and antioxidant properties. This study was conducted to determine the effect of chamomile aqueous extract on the productivity, egg quality, and serum biochemical parameters of laying Japanese quail. A total of 42 Japanese quail were separated into two groups of 21 birds each, with three replicates per group (7 birds) at random; the control group without any additives and the supplemented group with chamo...
Sarwat Yousuf1, Shaista Emad2 , Mohammad Misbah ur Rehman3, Zehra Batool4, Sara Qadeer5, Yousra Sarfaraz1, Sheeza Sheikh1, Sana Sadaf6 and Tahira Perveen1,*
...sed as an antioxidant, antibacterial and anti-inflammatory agent. This study intended to determine the potential role of lemon peel oil in neurobehavioral function and oxidative stress. Rats were treated with lemon peel oil at a dose of 0.7, 1.4, 2.1, 2.7, 3.5 g/kg for 14 days. Results showed that lemon peel oil at low doses has antidepressant and anxiolytic activity. Muscular strength was also improved at low doses. The brain antioxidant defense enzymes were ...
Amina Rahat1, Zahin Anjum1*, Sehlina Zehra2, Fatima Umal Baneen3 and Rabia Chishti1
...racts showed potential antibacterial, insecticidal and antifungal activities against different. The research has focused on the potential therapeutic efficacy of AliumSativum, NigelaSativa, and Plantago Ovata in the treatment of microbial infections due to their significant antibacterial activity. Additionally, Different fractions of the A. sativum, P. ovata, N. sativa were prepared anad analyzed for an...
Altaf Ur Rahman1, Muhammad Ajmal Khan2*, Ali Hazrat3, Awais Farid4, Muhammad Yahya3* and Inam Ullah5
...tii for phytochemical, antibacterial, antioxidant potential. The methanolic fraction of C. jacquemontii was evaluated for quantitative phytochemical constituents. The antibacterial efficacy was investigated via well diffusion method by using a concentration of 100 µg/ml. Furthermore, the antioxidant potential of extract was estimated at various concentration (50, 100, 150, 200, 250 µg/ml) through 2, 2-Diphenyl -1...
Maria Azam1, Tahir Mahmood Qureshi1, Saddam Hussain2, Amjad Islam Aqib3*, Shanza Rauf Khan4, Kashif Akram1, Misbah Ijaz5, Maheen Murtaza6, Afshan Muneer6 and Sammina Mahmood7
...nt strains were put to antibacterial testing assay against metallic nanoparticles both by well diffusion and broth microdilution method. To analyze the data, both probability and non-probability statistical tools were applied using SPSS version 22 of statistical software at 5% probability. The current study showed 24.56% of S. aureus positive from commercial dairy while the resistance of these isolates against gentamicin, enrofloxacin, levofloxacin, and vancom...
Tabark F Ahmed, Nibras Z. Yahya*
... exhibited synergistic antibacterial effects through fractional inhibitory concentration (FIC index < 1) against tested isolate, while the combination of ascorbic acid with erythromycin exhibited antagonistic effects. Furthermore, time-kill analysis showed that ASCORBIC/CIP combination exhibited highest synergistic and bactericidal effect. It was determined that in vitro study against E. coli O157 in the treatment of urinary tract infection, the combination...
Iram Liaqat1*, Noor Muhammad1, Muhammad Mubin2, Najma Arshad3, Tehreema Iftikhar4, Sumera Sajjad5 and Farzana Rashid5
...y aimed to explore the antibacterial and larvicidal potential of actinobacterial strains isolated from soil samples of Pakistan. Out of fourteen purified actinobacteria, antibiotic susceptibility profile confirmed five isolates showing resistance against tested antibiotics (ampicillin; lincomycin; rifampicin and erythromycin). Ribotyping confirmed that these isolates belong to Streptomyces species and were identified as S. monticola, S. septentrionalis, S. pol...
Eman M. Abdelhady1, Nader Y. Mostafa1, Mohammed A. El-Magd2* and Ghada A. Kirrella1
... CNPs exhibited higher antibacterial properties against S. aureus and E. coli, as revealed by lower minimal inhibition concentrations than the CP. Among these bacteria, E. coli was the most sensitive to CP and CNPs. Minced meat samples treated with CNPs showed significantly lower E. coli and total mesophilic counts than samples treated with CP. The pH values and antioxidant properties (as measured by the DPPH radical scavenging assay) of CNPs-treated samples w...
Frah Razzaq Kbyeh1, Ahmed N. Abedsalih2*
Orooba Mohammed Saeed Ibrahim1*, Rawaa Saladdin Jumaa2, Nibras Zeyad Yahya1
... aims to ascertain the antibacterial activities of fruit Citrus aurantium and Citrus limonum juice on isolated Staphylococcus aureus, Sterptococcus pneumoniae and Klebsiella pneumonia. The antibacterial activity of fruit juice extract on bacterial strain was determined using macro-broth dilution, agar well diffusion methods and time kill curve. Results revealed that the used juice extracts were variously bacteriostatic and ...
Aamir Ali, Hafiz Muhammad Tahir*, Azizullah, Shaukat Ali, Muhammad Farooq Bhatti, Muhammad Summer and Ali Haidar Gormani
...ammatory, antioxidant, antibacterial, anticancer, anti-diabetic and antidepressant activities. Further studies should explore the mulberry leaves potentials as these plants have got the attention of both the pharmacological and commercial industries.
Novelty Statement | The mulberry leaves possess various therapeutic potentials. In this study, we have summarized all the therapeutic potentials of diffe...
Raed Hussein Salih Rabee1, Yahya Sabah Abdulameer1, Walla Farhan Obed1, Noor R Abady1, Adnan Mansour Jasim1*, Firas Hussein Albawi1, Mohammed Jasim Jawad2, Ahmed Samir Abukhomra3
...berberine demonstrated antibacterial effects against E. coli, as well as anti-inflammatory and antioxidant properties. Furthermore, histopathological examination of the intestinal broiler received BBR showed improvements and restore tissue near to normal.
Keywords | Enerofloxacin, Berberine, E. coli, Antibiotic residues, CYP450, Antioxidant, Drug docking
...
Yunxia Guo1, Xia Zhou1*, Xin Huang2 and Fagang Zhong2
...al pathogens and their antibacterial resistance spectrum causing bovine respiratory tract infections in a large-scale cattle farm. Nasopharyngeal swabs were collected from animals (n=122) having clinical manifestations of respiratory tract diseases. Standard culture procedure followed by the Kirby-Bauer disc diffusion assay was applied to calculate the antimicrobial resistance profile of bacterial isolates. The survey results showed that bronchitis and broncho...
Sabi Ur Rehman1*, Laiba Arshad1, Saman Ali1, Shazma Massey2, Safeer Khan3, Abdul Samad4 and Fazal-Ur-Rehman5
...hy due to their potent antibacterial properties and relevance in nanomedicine. This study presents a green synthesis method using Sarcococca saligna leaf extracts to successfully produce both silver and gold nanoparticles. The formation and stability of the nanoparticles were verified through a change in physical colour and characterized using Ultraviolet-Visible spectroscopy and Scanning Electron Microscopy. Antibacterial a...
Khansa Jamil1, Muhammad Ramzan Khan1, Asad Jan2 and Ghulam Muhammad Ali1*
...as used to examine its antibacterial activity and phytochemical screening. Antibacterial assay was carried out by well diffusion method. A maximum number of compounds were eluted by methanolic extract by thin-layer chromatography and a total of 70 compounds were identified by GC-MS analysis. The phytochemical screening showed that the methanolic extract of the whole plant was rich in alkaloids and tannins. Zones of inhibitio...
Rabiea Pervaiz, Shaista Bano*, Sarfraz Ali Tunio, Abdul Nabi Jatt and Aisha Amber Soomro
...the discovery of novel antibacterial substances. However, some of the Bacillus species still remained to be explored widely for their antagonism against harmful bacteria. One of them is Bacillus pseudomycoides which produces rhizoidal colonies on solid medium. The present study was aimed to explore antibacterial properties of B. pseudomycoides isolated from the rhizosphere soil of the indigenous Mangifera indica (mango) plan...
Turrini Yudiarti*, Sugiharto Sugiharto, Endang Widiastuti, Hanny Indrat Wahyuni, Tri Agus Sartono, Maulana Hamonangan Nasution
...e nutritional quality, antibacterial properties and antioxidant activity.The obyective of this study was to see how adding the fermented product of the fungus Monascus purpureus as a feed additive affected to physiological parameters, intestine microbial population, and broiler internal organ weight. The method was one hundred and fifty un-sexed one-day-old chicks (DOC) were reared in an open cage. With three treatments, the study used a completely randomized ...
Rizqan*, Hilda Susanty, Linda Suhartati, Azhar, Arief, Elly Roza
...indings underscore the antibacterial potential of the citrus fruit peel eco-enzyme solution and suggest its viability as a natural and environmentally friendly teat dipping solution for dairy cattle.
...
...
Ahmed M. Manthoor, Ali H. Saliem*
...n the second step, the antibacterial effects of the extract as compared with ciprofloxacin, as well as zone of inhibition, minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC), by using 4, 8, 16, 32, 64 and 128 mg/ml concentration of the extract, while 1.562, 3.125, 6.25, 12.5, 25, 50, 100, 200, 400, 800 µg/ml concentration of Ciprofloxacin, on the other hand study mechanism of action of the extract against the same bac...
Tabinda Nowsheen1, Sayed Wadood Ali Shah2, Ali Hazrat1*, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar4 and Muhammad Ajmal Khan3
...ss the phytochemicals, antibacterial and antioxidant potential of the methanolic crude extract of leaves, stem, and roots of Artemisia maritime. The phytochemical screening of A. maritime leaves, stem and roots extract indicates the existence of flavonoids, terpenoids, saponins, tannins, phenolics steroids and carbohydrates but deficient of proteins. In minimum inhibitory concentration assay, the crude methanolic extracts showed significant inhibition against ...
Aalaa S. Saad1*, Taghreed H. A. Ali2, Nayerah Alatfeehy3, Dalia Elmasry4
...ve option owing to its antibacterial action against many pathogens in food. The aim of this study is to investigate the effect of propolis extract (PE) and propolis nanoemulsion (PN) on L. monocytogenes, its toxins’ expression, and the sensory qualities of breaded chicken panne during chilled storage. The 30% PN concentration had a size of 19.783 nm and a narrow size distribution (polydispersity index: 0.253) with a distinct chemical composition. PE&rsqu...
Aalaa S. Saad1*, Amira A. Elokle2, Dalia Y. Youssef2, Neven M. Omara2, Samr Kassem3
... aimed to evaluate the antibacterial activity of synthesized Chitosan nanoparticles (CS-NPs) and CS-LZ-NPs against E. coli O157 in chilled chicken fillets and relative eaeA (Intimin), stx2 (Shiga toxin) expression. The average particle size was 250 nm and 281.4 nm for CS-NPs and CS-LZ- NPs and the PDI (polydispersity index) was 0.09 and 0.58, respectively. TEM imaging showed uniformity and ranging in size from 13.1 to 17.6 nm and 15.6 to 19.5 nm for CS-NPs and...
SYED MUJTABA HAIDER1, KHIZAR HAYAT BHATTI1*, EJAZ HUSSAIN SIDDIQI1, SYED MAZHAR IRFAN1,`2, & ALLAH BAKHSH GULSHAN2
...was aimed to assess of antibacterial activity of ethanolic, methanolic and aqueous extracts of Aloe vera L. against six bacterial strains (Staphylococcus aureus; Streptococcus pyogenes; Shigella sonnei; Escherichia coli (1) (4C11); Escherichia coli (2) (ATCC 13048) and Neisseria gonorrhoeae). Agar well diffusion method was applied to assess the antibacterial activity of these extracts. Their antiba
SHAHZADA NADEEM ABBAS1, KIRAN JAMSHED1, SARAH BUSHRA NASIR2,
SAMAN SHAHID3 & NASIR MAHMOOD4
...robial activities. For antibacterial assays, the volume and concentrations of extracts used were 0.5 μl (62.5 μg), 1 μl (125 μg), 5 μl (625 μg) and 10 μl (1250 μg). Specific laboratory protocols of antibacterial and antifungal assays were adopted. Absorbance of the broth bacterial culture was measured after 72 hours by using photo spectrometer at the wavelength of 600 nm (A600). For antifungal assays,...
Muhammad Atif Raza1, Muhammad Tariq Javed2, Muhammad Fiaz1*, Muhammad Shakeel3, Muhammad Shahbaz Ul Haq2, Amna Kanwal2, Syeda Maryam Hussain1 and Muhammad Zubair Siddiqi4
Shah Zeb Khan1, Ali Hazrat1*, Farman Ali Khan2, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar3, Muhammad Ajmal Khan4 and Hayat Ullah1
...ential antioxidant and antibacterial properties. The crude was obtained in 95 % methanolic which was further fractionated into n-hexane (HR, HS), Chloroform (CR, CS), ethyl acetate (EtR, EtS) and butanol (BR, BS) soluble fractions by solvent-solvent extraction. In phytochemical tests of roots fractions; HR showed the presence of terpenoids, while saponins, alkaloids and flavonoids were detected in CR. EtR was enriched in terpenoids and phenols and the butanol ...
Kiran Rani1*, R. Aliya1, Barkat Ali Solangi2, M. Kashif Pervez2, Nasrullah Akhtar3 and Farman Ahmed4*
...mpared with commercial antibacterial and antifungal drugs. It was found at the optimized dyeing condition has 1 percent formic acid as fixing agent with 120 min dyeing period. At this condition, the dye molecule shows 70 percent exhaustion and 59 percent fixation along with acceptable fastness and antimicrobial activities Furthermore, the dyed fabric shows effective inhibition against all tested organisms. Fabric samples showed greater antimicrobial efficiency...
Syeda Fakehha Naqvi1, Iqra Haider Khan1 and Arshad Javaid1
...ssed antifungal and/or antibacterial properties while very few of them also possessed antioxidant potential. This study concludes that n-hexane soluble fraction of methanolic stem extract of C. murale is a big storehouse of antimicrobial compounds....
*Arshad Javaid1, Syeda Fakehha Naqvi1 and Iqra Haider Khan1
...ntifungal,
antibacterial, antioxidant, anticancer and antipsoriatic. However, this study concludes that
most of the compounds were antimicrobial in nature.
...
Irum Mukhtar,Sobia Mushtaq,Amna Ali,Ibatsam Khokhar,MUHAMMAD SALEEM HAIDER,SHABNAM JAVED
Editor
... foresters,
farmers,'attibas' and personals engaged
in the manufacturer of medicines used in
the traditional system, to initiate
discussion among them for the promotion,
conservation and use of drug plants on
scientific lines, marketing, processing
and involvement of the end users i.e.
industrial manufacturers....
Hafsa Tauqir1, Imran Ahmad2 and Muhammad Bilal Sadiq1*
...tion optimization. The antibacterial activity of the pomace extract was tested against Escherichia coli, Salmonella typhimurium and Staphylococcus aureus by agar well diffusion method and the zone of inhibitions observed were 29.7±0.6 mm, 31±1 mm and 30±3 mm respectively. Yogurt samples fortified with extract (2% and 4%) were prepared and underwent sensory evaluation for characteristics such as color, odor, texture, acceptance of sourness ...
Shabana Islam1, Shahida Shujaat1*, Erum Akbar Hussain1, Mateen Abbas2
...he additional in vitro antibacterial activity of the samples against two Gram positive bacteria (Staphylococcus aureus, Bacillus cereus) and three Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhimurium). The effectiveness of the samples was greater against Gram positive bacteria (MIC = 0.3 mg/mL) compared to Gram negative bacteria (MIC = 0.9 mg/mL). Upon testing the synergy between Ciprofloxacin and one of the samples, it ...
Javairia Mehboob1, Syeda Hafsa Ali1*, Fahima Ashraf Kasi1, Syeda Ayesha Ali2, Safa
Farooqi3, Muneeza Arbab4,
... with size <100 nm. Antibacterial activity of lavender mediated AgNP was highly
significant, followed by artichoke mediated AgNP and Alkanet AgNP. However, in contrast,
Artichoke mediated AgNP showed significant activity against plant fungal strains, followed
by Alkanet AgNP, and finally by Lavender mediated AgNPs. We concluded that the three
plants have versatile biochemical molecules responsible for wide ran...
*Arshad Javaid1, Iqra Haider Khan1 and Malik F. H. Ferdosi2
...antitumor, antifungal, antibacterial, antioxidant,
anticancer, anti-inflammatory, antidiabetic, and analgesic.
...
Suhair Sh. Al-Siraj1, Jihan M. Badr2 and Dalia M.A. El-Masry3*
...his study examined the antibacterial effects of Bay leaf (laurusnobilis) aqueous extracts and nano-emulsion against gram-positive (Staphylococcus aureus) and gram-negative (E. coli and Pseudomonas aeruginosa) bacteria and their effects on virulence and antibiotic resistance genes. The MIC) minimum inhibitory concentration (of both was determined using thiazolyl blue tetrazolium bromide (MTT) micro dilution to assess antibact...
Qais Abdulrahman M. Al-Jaghifi, Zina Saab Khudhir*
...ness of chitosan as an antibacterial agent against methicillin-resistant Staphylococcus aureus (MRSA) isolated from frozen and fresh beef was evaluated. Bacterial isolates were confirmed using cultural, biochemical, and the VITEK 2 system. All suspected MRSA isolates tested positive for MRSA. In frozen meat samples (n=50) collected from different markets in Baghdad city, the number and isolation percentage (%) of S. aureus and MRSA were 11/50 (22%) and 4/50 (8...
Sohaila Fathi El-Hawary1, Nermeen M.L. Malak2, Reda A. Gomaa3, Hesham Z. Tawfeuk3, Suzan Ismail4, Nady Khairy Elbarbary5*
...tance profile, and the antibacterial influence of lemon juice and pomegranate peel extract on V. cholerae and V. parahaemolyticus. Samples were 150 fish (30 of each Nile tilapia, Nile perch, sardine, Mugil cephalus, and Sea bass) from fish supermarkets. Sardine samples had the highest Vibrio count (4.77±1.22 log10 CFU/g), followed by and Sea bass (4.62±1.35 log10 CFU/g), Mugil cephalus (3.50&plusm...
Afnan Ahmed Allhyani1, Mohamed Baeshen1, Nagwa Thabet Elsharawy2,3*
...tives by examining its antibacterial effect by (aquas & ethanolic) extracts by different concentrations (1.25, 2.5, 5, 7.5, 10, 12.5 & 15) cc against six foodborne microorganisms (Listeria monocytogenes, Staphylococcus aureus, Salmonella typhi, Escherichia coli, salmonella enteritidis and Vibrio parahaemolyticus). Finally, the different concretions of each extract were added to the chevon. Obtained results observed that all extracts have an
Bunga Rimta Barus1, Masfria Masfria2*, Aminah Dalimunthe3, Sovia Lenny4
... exhibited significant antibacterial activity against Staphylococcus aureus, with the 5% concentration showing the largest zone of inhibition (11.20 ± 0.30 mm). Histological analysis revealed that the 5% gel concentration significantly enhanced epidermal thickness (52,407.77 ± 1.34 nm) and promoted angiogenesis (26.33 ± 0.31) in the wound area. These results indicate that the 5% ethyl acetate fraction gel is the most effective in promoting...
Mohamed Ahmed Abaza1, Amany O. Selim2, Mona Abdallah3, Shimaa A.E. Atwa4, Hala El Daous5, Mona Abd-Allah Abd-Elrehim6, Mohamed M.S. Gaballa7, Reda R. Fathy1*
...chicks to evaluate the antibacterial effectiveness of 50mg/kg ration dosage compared with colistin as commercial antibiotic at 5 days old. E. coli serotype O6 was the highest prevalent and pathogenic multi drug resistant bacterial strain.The assessment parameters were clinical signs, post-mortem lesions and histopathological picture which showed effective role of ZnO-NPs as bacterial inhibitor in the treated groups compared to control one. Quantitative analysi...
Nasr Tarq Mohammed
...ess anti-carcinogenic, antibacterial, antifungal, antiviral, and immune-boosting properties. This study aimed to evaluate the anticancer potential of aqueous garlic extract (AGE) against breast cancer cell lines. The use of a simple aqueous extract allows for easy and cost-effective preparation while retaining bioactivity. In this research, the effectiveness of AGE in inhibiting cancer cell viability was assessed using cancer cell lines CAL51 and AMN3. The cel...
Mustofa Hilmi1,4, Zuprizal2, Nanung Danar Dono2, Bambang Ariyadi3*
...: justify;">Keywords | Antibacterial, Antibiotic, Minimum inhibitory concentration, Nanotechnology, Optical density, Silver nanoparticles
...
Rico Anggriawan1*, Widya Paramita Lokapirnasari2, Sri Hidanah3, Muhammad Anam Al Arif4, Diyah Ayu Candra5
...h a combination of the antibacterial agents enrofloxacin and tylosin, that work together in their mechanism of action and have synergistic action in the antibacterial spectrum . Tylosin is a broad-spectrum macrolide antibiotic, while enrofloxacin is a broad-spectrum fluoroquinolone antibiotic. On commercial poultry farms in Indonesia, the combination of enrofloxacin and tylosin Tylosin and enrofloxacin are often used togethe...
Safaa El Bialy1*, Nabil Bker2, Hossam Ibrahim3, Saber, A. Saad4, Eman Ali5
... their antioxidant and antibacterial properties.
Keywords: Parsley oil-Fish fillet, Biogenic amine, Enterobacteriaceae, Coliform
...
Shaymaa Jabbar Hassoon1*, Hiba Ibrahim Ali2, Ayat Jasim Mohammed3, Oras Salman4
...as done to examine the antibacterial properties of silver nanoparticles synthesized from cinnamon extract against bacteria isolated from fresh sheep meat. Silver nanoparticles were synthesized by mixing 1ml of Cinnamon extract (0.025) % with (50ml) of silver nitrate solution (1.25)% and the ratio was (1:50) (v:v) at room temperature for (8hrs.) with pH(6.5-7) , later 8hrs, A higher pigment amount was seen. The physical features of AgNPs were proved...
Abeer S. Hafez1, Shereen M. Aly1, Dalia M. A. Elmasry2*, H. A. Hussein3, Marwa A. Abdelmagid4
...sorbed and have better antibacterial and antifungal effects than ordinary propolis. The present study aimed to compare propolis ethanolic extract (PEE) and propolis nanoemulsion (PN) as a feed additive in poultry farms by evaluating their influences on growth, immune status, and pathological conditions in chickens. The size, uniformity, and spherical shape of PN were measured at 4.065 ±1.12nm, with a polydispersity index of 0.021 which allows for easy b...
Sehar Aslam1, Muhammad Qasim1*, Mohsin Khurshid2*, Usman Ali Ashfaq1 and Muhammad Akhtar Ali3
...sponse, enhancement of antibacterial and anti-allergic properties, as well as anti-proliferative properties. These beneficial microorganisms can interact with the gut microbiota to restore an impaired gut microbiome. While probiotics can be sourced from various sources, this study focuses on isolating and characterizing novel probiotic strains from dairy sources, specifically Dahi. To evaluate the probiotic potential of these isolates, various biochemical, mor...
Mohamed E. Enany1, Ahmed M. Hamouda2, Reem M. Khashaba3*
...ct display significant antibacterial activity (MIC 64 μg/ml), but it modulated the activity of amoxicillin and doxycycline and florophenicol with MIC 32 μg/ml,32 μg/ml and 16 μg/ml in order, i.e. in combination with amoxicillin, 2fold (8 μg/ml) reduction in the MIC value at the ratios 9:1,8:2and 7:3 of combination against E. coli and 1fold with Salmonella typhimurium and Klebsiella pneumoniae was observed at same ratios. While rosemary deacrease...
N. M. Abed
...ammatory, anti-cancer, antibacterial and hepatoprotective properties. Propolis protects thyroid and gonadal function from NiCl2 and CCl4. In order to assess the protective impact of propolis extract against NiCl2 and CCl4, 80 adult male albino rats were divided into eight groups including control group, the propolis-treated group, the NiCl2-treated group, the CCl4-treated group, the NiCl2 and propolis-treated group and the CCl4 and propolis-treated group. Bloo...
Trang Nguyen Phan*, Loc Bao Nguyen, Thi Anh Ngoc Tong
...llus fermentum, Lactiplantibacillus plantarum, Weissella confusa, and Weissella paramesenteroides. The differences in LAB species found in meat versus vegetables-fermented foods reflect these bacteria’s adaptability and ecological variation. These data are anticipated to serve as valuable documents for further monitoring the resistance patterns of LAB in fermented foods.
Keywords | Lactic acid bacteria, Antibiotics resistan...
H.A. Abdul-Ratha1*, Sahar Mahdi Hayyawi2, Essam F. AL-Jumaily3
...xtreme temperature and antibacterial drugs. The aim of the current study is to evaluate the effect of purified acidocin (alone) that produced by Lactobacillus acidophilus isolates or with biofilm extract produced by Staphylococcus aureus, on cell permeability and mode of action on cell structure under scanning electron microscope. Forty eight Staphylococcus aureus isolates were diagnosed from the total 142 cows milk samples collected from different areas.These...
Afshan Kaleem*, Iqra Noor, Roheena Abdullah and Mehwish Iqtedar
...saponins, phenols etc. Antibacterial analysis of aqueous extracts of Phaseolus vulgaris and Vigna unguiculata were done by using the disc diffusion method, which showed that both extracts have potential antibacterial activity against Staphylococcus aureus and Escherichia coli, though Phaseolus vulgaris has higher antibacterial activity than Vigna unguiculata. FTIR and in silico analysis sh...
Malik F.H. Ferdosi1, Arshad Javaid2*, Muhammad Samiullah1, Zeeshan Mutahir3 and Tajamal Hussain4
...cal properties such as antibacterial, antifungal, acaricidal, antioxidant, anticancer, nematicidal, antiacne, insectifuge, antiarthritic, antihistaminic, anti-inflammatory and antieczemic hepatoprotective....
Madeeha1, Shahida Naveed1*, Ayosha Hanif1, Jalwa Afroz1, Abdul Haq1, Gul Rose2, Inayat Ullah3 and Zunaira Inayat4
...research in developing antibacterial and antifungal agents....
Dadile M. Abdulrahman 1 Abdullahi M. Daskum 1 Kura M. Abdulrahim 1 Abubakar M. Dadile 2 Hajja Amma 3
Volume 1, Issue 1, November and December 2017, Pages 3-13
...ide effects....
Mahesh Raj Pant 1 Dipti Shrestha 1 Shovana Thapa 2
Volume 2, Issue 3 May and June 2018 Pages 53-60
...ere the most effective antibacterial drugs. Out of total 75 S. aureus isolates, all were reported to be susceptible to Vancomycin, whereas, 23 (30.7%) were resistant to methicillin. This study reported that S. aureus strains were the predominant isolates. Prevalence of multi-drug resistant strains of S. aureus is increasing. Current results demonstrated that antibiotic resistance in Gram-positive and Gram-negative bacteria is increasing in alarming trends that...
Solange Gahongayire 1 Ibrahim Ntulume 1 Kagimbura Ervine 2 Bizimana Évariste 2 Adamu A. Aliero 3
Volume 2, Issue 6 November and December 2018 Pages 156-166
...med at determining the antibacterial activity of ethanolic crude extracts of leaves and fruits of Capsicum annum against Staphylococcus aureus
Yasir Iftikhar1*, Talha Shafique2, Shahzaib Asghar1, Sonum Bashir3, Malik Abdul Rehman4, Maham Ikram1, Muhammad Ahmad Zeshan1, Farwa Seemab1, Komal Ambreen1 and Ashara Sajid1
...phasizing the powerful antibacterial qualities of Clove oil. Cinnamon oil also demonstrated inhibitory effects like clove oil but to a lesser extent. The outcome of this study is to encourage the use of essential oils as biological control and find out if plants show toxicity against pathogens. Since essential oils include a variety of antimicrobial components, we must use them to their fullest potential and assess how best to incorporate them into various int...
Fatiha Malki1*; Abdelkader Touati1
Novel Research in Microbiology Journal (2019), 3(1): 281-285
...de 2 demonstrated high antibacterial activity against P. aeruginosa, and was more active against S. enteric than substituted fatty amide 1. On the basis of these obtained results, it could be assumed that fatty amide derivatives may be used as components of disinfectants, and may be possible sources of new drug...
Taher A. Salaheldin1,2; Ghadir A. El-Chaghaby3*; Mohamed A. El-Sherbiny3
Novel Research in Microbiology Journal (2019), 3(1): 215-222
...s used to evaluate the antibacterial activity of AgNPs against Bacillus subtilis, Escherichia coli, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus faecalis. Cytotoxic activity of biosynthesized AgNPs was tested against humane breast cancer cell line (MCF-7). Results of characterization showed that AgNPs were irregular spherical in shape, with average diameter of 27.41nm, and width of 4.36nm. The an...
Mahmoud Saber Kelany1*; Ehab Aly Beltagy2; Maha Abd El-Fattah Khalil3; Mohamed Ahmed El-Shenawy2; Wagih Abd El-Fattah El-Shouny3
Novel Research in Microbiology Journal (2019), 3(1): 258-270
...determine the in vitro antibacterial activity of the active compound produced by this bacterium; whereas, GC-MS analysis was used to identify the components of this bioactive substance. GC-MS analysis showed that the active principle might be Phthalic acid, octyl 2-pentyl ester with retention time of 23.13 min. Crude extract of Bacillus sp. MK20 at a concentration of 200 mg/l exhibited LC50 of 2.5 ppm against Artemia salina. The aims of the current work were; ...
Abeer, F. Ahmad1*; Afaf, O. Ali1
Novel Research in Microbiology Journal (2019), 3(2): 286-296
...s natural colorant and antibacterial additives in Rayeb milk. Citric acid: ascorbic acid (2:1) (BCA) and citric acid (0.2%) (BC) were used as extraction solvents of beetroot. Antibacterial activity; minimum inhibitory concentration (MIC), minerals content (calcium, iron, phosphorus, potassium, and selenium), and phytochemical screening were determined in BCA and BC extracts. Moreover, the antiba
Shaimaa A. Elbadri1*; Marwa S. Fathi1; Amira E. Abdel Hamid1; Hanaa A. ElGendy2
Novel Research in Microbiology Journal (2019), 3(4): 428-439
...biotics, with reported antibacterial and anti-biofilm activity against many different pathogenic microorganisms. This study aimed to study the potential antibacterial and anti-biofilm effect of Lactobacillus acidophilus ATCC 4356, against the growth and biofilm formation of pathogenic P. aeruginosa. Cell free supernatant of L. acidophilus was tested to inhibit the growth; biofilm formation, and on preformed biofilms by 35 di...
Zakaria Ahmed1
Novel Research in Microbiology Journal (2019), 3(6): 485-492
...ompounds with possible antibacterial effects. It is employed largely due to its antimicrobial properties, and is incorporated as the active ingredient in many topical formulations used to treat cutaneous infections, in addition to being marketed as a remedy for various ailments. The essential oil of M. alternifolia exhibits broad-spectrum antimicrobial potential. The TTO may help to treat severe yeast infections. Results also suggested that TTO exerts a greate...
Andriantsihoarana J. Razanatseheno1; Lovarintsoa J. Randriamampianina1; Hanitra R. Randrianarivo1; Danielle A. D. Rakoto1; Victor L. Jeannoda1*
Novel Research in Microbiology Journal (2019), 3(6): 502-510
...tudy was to assess the antibacterial potential of Albizia mahalao, a Madagascar Fabaceae. Leaf methanolic extracts (LME), root bark methanolic extract (RME), stem bark methanolic extract (SME), and alkaloids extracted from leaves under basic and acidic conditions were used. All the methanol extracts contained alkaloids and saponins. The antimicrobial activity was tested against many bacteria spp. including; Listeria monocytogenes, Staphylococcus aureus, Clostr...
Dalia G. Ali1; Gamal F. M. Gad1; Osman A. O. Ismail2; Hala R. Ahmed1*; Reham A. Ibrahem1
...s spp.
The antibacterial sensitivity of the Proteus spp. was examined using 16 different antibiotics
from various families. The most effective antibiotics were Amikacin; Levofloxacin, and
Meropenem, recording 68.6 %, 66.2 %, and 62.2 % of the isolates sensitivity to each of these
antibiotics, respectively. Using the ureR-based PCR, 48 % of the isolates were identified as P.
mirabilis. Moreover, the Qn...
Noha Mostafa Mahmoud*
...
discovering new antibacterial agents and resistance genes. The aim of this review was to
highlight the background; methodologies, and future use of culturomics to study the human
gut microbiota.
...
Anjana Suresh*; Grasian Immanuel
...microbial;
antibacterial, and antifouling activity. During the screening of antifouling compounds; these
marine microorganisms displayed antifouling ability against the macro and micro-foulers. This
review aimed to focus on the improvements in the antifouling abilities of the natural products
derived from marine organism-associated microorganisms.
...
David C. Nwobodo1,5*; Chibueze P. Ihekwereme2; Chinedu J. Ikem3,5; Festus B.C. Okoye4
Novel Research in Microbiology Journal (2020), 4(3): 845-855
...arcinia kola for their antibacterial activities against P. aeruginosa. The endophytic fungi associated with healthy leaves of G. kola were isolated using the standard methods. These fungi were subjected to solid-state fermentation on rice media at 28oC for 21 d. The fungal secondary metabolites were extracted using ethyl acetate, and then concentrated under vacuum. The fungal crude extracts were screened for their antibacter...
Yasmine Abdallah; Ranya M. El-Ashmony; Abdelrazek S. Abdelrhim*
Novel Research in Microbiology Journal (2020), 4(4): 939-954
Maysaa, T. Alloosh1*; Walid, I. Khaddam1; Adbulsalam, K. Almuhammady2
Novel Research in Microbiology Journal (2021), 5(1): 1077-1090
...ger. Moreover, NPs has antibacterial efficacy against Staphylococcus aureus and Pseudomonas aeruginosa, which recently become less affected by several antibiotics like penicillin and methicillin. This review will help the researchers who work in biosynthesis of NPs and in the nano-medical application fields....
Zeinab, S. Hashem1*; Rehab, M. Abd El-Baky1,2
Novel Research in Microbiology Journal (2021), 5(1): 1091-1105
...med to investigate the antibacterial and antibiofilm activities of Lactobacilli isolated from fecal microbiota of healthy infants; to identify these isolates and determine their probiotic characteristics. E. coli isolates were recovered from urine samples of patients with urinary tract infections. On the other hand, Lactobacillus isolates were recovered from feces of breast-fed infants. Five strong biofilm forming E. coli isolates with multidrug resistance (MD...
Rasha M. Elnagar
Novel Research in Microbiology Journal (2021), 5(2): 1194-1213
...ter spp. 3 (3.6%). The antibacterial sensitivity testing of the total 178 bacterial isolates was assessed using the disc diffusion assay. Bacterial pathogens that were carbapenemase producers were tested using phenotypic, rapid colorimetric (Carba NP test) and genotypic methods. Among these isolated bacteria 31 (83.8%), 26 (70.3%) and 28 (75.7%) were carbapenem resistant; confirmed by MHT, Carba NP test and multiplex Polymerase chain reaction (PCR), respective...
Nouran H. Assar1*; Aya allah T. Mohamed2,3; Rehab M. Abd El-Baky2,3; Reham Ali Ibrahem2
Novel Research in Microbiology Journal (2021), 5(3): 1256-1268
...valuate their in vitro antibacterial potential against human pathogens; namely Staphylococcus aureus (Staph. aureus) and Escherichia coli (E. coli). Nanoparticles (NPs) are becoming popular in different fields of research, and are useful in combating vast number of microbial diseases. NPs may be artificially synthesized in vitro using chemical methods and\or via extracellular metabolites produced by the bacterial strains. In the present study, biosynthesis of ...
Ghadah A. Alsubhi1,2*
Novel Research in Microbiology Journal (2021), 5(6): 1405-1414
...t of bacteriophages as antibacterial agents was known after their first discovery in 1915, and they were then employed to treat the bacterial infections. However, the discovery of penicillin in 1928 quickly overshadowed bacteriophage therapy, and paved the way for its large-scale production in the 1940s to enter the era of antibiotics. In recent years, resistant bacteria have contributed to increasing the studies on bacteriophages. A remarkable difference betw...
Noura El-Kattan1*; Kamilia A.M. Allam2
Novel Research in Microbiology Journal (2021), 5(6): 1447-1462
...ducted to evaluate the antibacterial activity of nano-encapsulated essential oils of basil (Ocimum basilicum) and cinnamon (Cinnamomum verum) against multidrug-resistant (MDR) bacteria. A total of 115 wound swab samples were collected from patients admitted to Naser Institute, Cairo, Egypt, suffering from wounds discharge; pain, swelling, foul-smelling, delayed and non-healing wound infections. Six genera of bacteria were isolated from the collected swab sampl...
Salwa Mahmoud Masoud1; Rehab Mahmoud Abd El-Baky1,2; Sherine A. Aly3; Reham Ali Ibrahem1*
Novel Research in Microbiology Journal (2022), 6(2): 1543-1556
...ere the most effective antibacterial antibiotics. The current results showed statistically significant association of the tested genes, as 89 % of the E. coli isolates harbored more than one gene. This study highlighted a public health concern; as the elevated antibiotic resistance narrowed the therapeutic options and led to the failure of treatment of such bacterial infections....
Vinita C. Patole1*; Jayashri G. Mahore1; Tanaji D. Nandgude1; Anil Gutte1
Novel Research in Microbiology Journal (2022), 6(4): 1659-1669
...rted to exhibit potent antibacterial activity. ACV also contains lactic acid bacteria, which can act as probiotics. Symptoms of AV can be improved by restoring the disturbed microbial imbalance rather than exposing the vagina to synthetic drugs. Hence, an attempt was made to investigate whether ACV could support growth of the beneficial bacteria and inhibit growth of the pathogenic bacteria such as E. coli in the vagina. In vitro evaluation of the anti-bacteri...
Fatma Ahmed Abdel Aziz1; Gamal Fadl Mahmoud Gad1; Ahmed Mohamed Kamal El Shafei2; Reham Ali Ibrahem1*
Novel Research in Microbiology Journal (2022), 6(5): 1725-1741
...itis, as well as their antibacterial susceptibility patterns. In addition to emphasizing on detecting the predominance of certain virulence genes of Methicillin Resistant Staphylococcus aureus (MRSA), and Methicillin Resistant coagulase negative Staphylococci (MR-CoNS), which are known to cause conjunctivitis. In this study, several swabs of bacterial conjunctivitis were sampled from patients who attended to the Ophthalmology department, Minia University and M...
Amal Nasser Alahmari1*; Shahira A. Hassoubah1; Bothaina Ali Alaidaroos1
Novel Research in Microbiology Journal (2022), 6(5): 1742-1767
...ndary metabolites with antibacterial or antifungal efficacy have been recovered from marine bacteria derived from sponges; they have been used as potential sources of antimicrobial compounds and might be promising sources that can be exploited in the future for several pharmaceutical purposes....
Amal Nasser Alahmari1*; Shahira A. Hassoubah1; Bothaina Ali Alaidaroos1
Novel Research in Microbiology Journal (2022), 6(5): 1742-1767
...ndary metabolites with antibacterial or antifungal efficacy have been recovered from marine bacteria derived from sponges; they have been used as potential sources of antimicrobial compounds and might be promising sources that can be exploited in the future for several pharmaceutical purposes....
Ghadir A. El-Chaghaby; Heba A. Shehta; Sayed Rashad; El-Shaimaa A. Rawash; Heba R. Eid
Novel Research in Microbiology Journal (2024), 8(1): 2303-2319
...tionally, the in vitro antibacterial efficacy of the extracts against several food-borne bacterial strains revealed that spent coffee ethanolic extract was effective against all the tested bacteria with inhibitory percentages ranging from 34.62 to 66.69 %, whereas the aqueous extract expressed an inhibitory effect only against Salmonella typhimurium (35.82 %). To assess the practical utility of SCE as food preservatives, chicken fillets were treated with SCE a...
Apoorva Jain1; Ajay Kumar Oli1*; Sughosh Kulkarni2; Raghavendra D. Kulkarni2; Kelmani Chandrakanth3
Novel Research in Microbiology Journal (2024), 8(3): 2435-2451
...echanisms underpinning antibacterial resistance in ESKAPE bacteria is paramount for developing effective interventions. Enhanced insights into these mechanisms will facilitate the prediction of resistance patterns among the multidrug-resistant pathogens, thereby guiding the development of targeted therapies and preventive measures. Consequently, comprehensive efforts are needed aiming at unraveling the intricacies of antibac...
Zine El Abidine Bzazou El Ouazzani1; Laila Reklaoui1; Houda Benaicha1,2; Said Barrijal1*
Novel Research in Microbiology Journal (2024), 8(4): 2491-2509
...f enhancing colistin's antibacterial and antibiofilm activities (FICI ≤ 0.5). The investigation focused on eight colistin-resistant (CS_R) bacterial isolates, with a particular focus on two strains carrying the mobile colistin resistance mcr-1 gene. The CS@OM combination resulted in a 2- to 16-fold improvement of colistin efficacy, resulting in a biofilm eradication rate ranging from ∼ 52 % to 82 %. Furthermore, it evinced a complete eradication of the ...
Fateh Merouane1*; Amani Kifadji2; Racha Mansouri3; Meroua Safa Mechouche1,4; Chemes El-Houda Messaad5,6; Anfal Bellebcir1
Novel Research in Microbiology Journal (2024), 8(5): 2555-2579
...production of valuable antibacterial compounds from Streptomyces species and contributed to the global efforts to combat antimicrobial resistance....
Mai N. Amer1; Maissara M.K. Elmaghraby2; Aya A.M. Abdellatif2; Sondos R. Salem3; Mariam M. Salama3; Omar A. Abdel Maksoud3; Radwa M. Nasr3; Mohamed N.H. Amer4; Mohamed M.H. Marghany5; Hassan M. Awad1*
Novel Research in Microbiology Journal (2024), 8(5): 2580-2603
...xopolysaccharides with antibacterial attributes. Consequently, probiotics are utilized in food technology to develop the functional foods that promote the human health....
Subhasmita Mallik1; Samikshya Nayak1; Arpita Panda2; Smrutirekha Behera1; Kamalakanta Swain2; Archita Patra1; Rukmini Mishra1; Jatindra Nath Mohanty1*
Novel Research in Microbiology Journal (2024), 8(5): 2604-2631
...ssary to explore their antibacterial attributes. Specifically, transcriptome profiling should be employed to identify therapeutic molecules from plant-based products that can effectively combat MDR bacteria before synthesis of nano-drugs. The outcomes of this study will enable the researchers to obtain the best approaches to tackle MDR pathogens through using the nano-based phytochemicals....
Sarah Sonbol1; Nahla A. Hussein2*
Novel Research in Microbiology Journal (2024), 8(5): 2653-2665
...tance to commonly used antibacterials, including cell envelope acting antibiotics, aminoglycosides, quinolones, and sulphonamide. The resistance genes showed different distributions among the core, dispensable and/or strain-specific genomes, ranging from an almost equal distribution in E. coli and S. enterica to higher occurrence in the dispensable/ strain specific genome in K. pneumoniae. Depending on the bacterial genus, cell envelope acting antibiotics occu...
Amany A. Hassabo1; Basant A. Ali1; Shaimaa A. Tawfik2; Hossam E. Emam3*
Novel Research in Microbiology Journal (2024), 8(5): 2666-2682
...nts for drug delivery, antibacterial, and anticancer treatments due to their significant permeability and retention effects. Both of nano-size copper (Cu) and selenium (Se) exhibited a significant activity in biological treatment and drug delivery systems. Consequently, the present work aimed to focus on the novel biogenic synthesis of Cu-Se BNPs using cell-free extract of a marine bacterium, and studying their anticancer and antioxidant activities. Based on 1...
Tran Thi Hong1; Ngo Van Anh1; Nguyen Thi Ngoc Anh2; Nguyen Van Phuong3*
Novel Research in Microbiology Journal (2024), 8(6): 2694-2711
... genes were related to antibacterial, antifungal, antiviral, cancer cell inhibition, and antioxidant activities. This is the first study conducted on lagoon microorganisms in Vietnam, opening up prospects and potential in exploiting microorganisms and biologically active substances with important applications in life from the lagoon ecosystems of Vietnam in particular and the overall world in general....
Aml Ghanem1,2; Ahmed A. Al-Karmalawy3,4; Noha E. Morsy5; Mahmoud Elsabahy6; Ahmed M. Rayan2,7*
Novel Research in Microbiology Journal (2024), 8(6): 2750-2771
...ative or complementary antibacterial agent; particularly in situations where antibiotic resistance is a concern. DCM extract exhibited moderate cytotoxicity with an IC50 of 70 μg/ ml compared to the more potent Doxorubicin with an IC50 of 10 μg/ ml. This suggests that Alternaria alternata extract may offer a less aggressive alternative for cancer therapy. Docking results revealed that key secondary metabolites such as dihydroaltersolanol showed strong bi...
Noura Sh. A. Hagaggi1*, Marwa E.A. Khalaf2 and Eman A. El Rady2
...racts displayed strong antibacterial efficacy against Salmonella typhi, Staphylococcus aureus, and Klebsiella pneumoniae. Furthermore, the antioxidant activity of the extracts ranged from 47.12± 1.68 to 103.6± 3.8 µM Trolox equivalent/ μg extract, scavenging the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radicals by 43.66-90.21 %. This study highlights the potential of the endophytic bacteria associated with H. muticus as substitute producers ...
